Evidence map›Paper›PMID 37994695›Full record

ArticleBrain pathology (Zurich, Switzerland)2024

Two novel tumours with NTRK2 fusion in the methylation class of extraventricular neurocytomas, including one intraventricular.

Emmanuelle Uro-Coste, Arnault Tauziede-Espariat, Charlotte Dubucs, Dan Christian Chiforeanu, Aurore Siegfried, Yvan Nicaise, Luc Bauchet, Laurent Riffaud, Franck Bielle, Alexandre Vasiljevic and 5 more

Abstract readLetter
In one paragraph

Article in Brain pathology (Zurich, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Emmanuelle Uro-CosteDepartment of Pathology, Toulouse University Hospital, Toulouse, France.ORCID 0000-0001-7300-5724
Arnault Tauziede-EspariatGHU Psychiatrie et Neurosciences, Site Sainte-Anne, Service de Neuropathologie, Paris, France.ORCID 0000-0002-9979-0297
Charlotte DubucsDepartment of Pathology, Toulouse University Hospital, Toulouse, France.
Dan Christian ChiforeanuDepartment of Pathology, Rennes University Hospital, Rennes, France.
Aurore SiegfriedDepartment of Pathology, Toulouse University Hospital, Toulouse, France.
Yvan NicaiseINSERM U1037, Cancer Research Center of Toulouse (CRCT), Toulouse, France.
Luc BauchetDepartment of Neurosurgery, Montpellier University Hospital, Montpellier, France.
Laurent RiffaudDepartment of Neurosurgery, University Hospital, Rennes, France.
Franck BielleDepartment of Neuropathology, AP-HP, Hôpitaux Universitaires Pitié-Salpêtrière Charles Foix, Paris, France.ORCID 0000-0001-6564-6388
Alexandre VasiljevicDepartment of Neuropathology, Groupe Hospitalier Est, Hospices Civils de Lyon, Bron, France.
Romain AppayAPHM, CHU Timone, Service d'Anatomie Pathologique et de Neuropathologie, Marseille, France.
Solène EvrardDepartment of Pathology, Toulouse University Hospital, Toulouse, France.
Pascale VarletGHU Psychiatrie et Neurosciences, Site Sainte-Anne, Service de Neuropathologie, Paris, France.
Valérie RigauInstitute for Neuroscience of Montpellier (IGF), INSERM U1051, Montpellier University Hospital, Montpellier, France.
Biopathology RENOCLIP‐LOC network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here about two novel tumours classified as extraventricular neurocytomas (EVN) using DNA-methylation profiling, associated with NTRK2 fusions instead of the usual FGFR1 alterations so far attributed to this tumoural entity. We present the second detailed case of an intraventricular presentation in the MC EVN. Our findings broaden the spectrum of MC EVN and have implications in terms of diagnosis, therapy and terminology.

Indexed as

Brain NeoplasmsNeurocytomaHumansMethylationReceptor, Fibroblast Growth Factor, Type 1Receptor, Fibroblast Growth Factor, Type 1

Identifiers

PMID37994695
PMCPMC11006991

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.