Evidence map›Paper›PMID 37994538›Full record

Trial reportInfection control and hospital epidemiology2024

Alcohol-based decontamination of gloved hands: A randomized controlled trial.

Kerri A Thom, Clare Rock, Gwen L Robinson, Heather R S Reisinger, Jure Baloh, Emily Chasco, Yuanyuan Liang, Shanshan Li, Daniel J Diekema, Loreen A Herwaldt and 3 more

Open access · hybridAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Infection control and hospital epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Kerri A ThomDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
Clare RockDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University, Baltimore, Maryland.
Gwen L RobinsonDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0002-4701-1159
Heather R S ReisingerUniversity of Iowa Carver College of Medicine, Iowa City, Iowa.ORCID 0000-0002-5348-063X
Jure BalohDepartment of Health Policy and Management, University of Arkansas for Medical Sciences, Little Rock, Arkansas.ORCID 0000-0002-7356-8313
Emily ChascoUniversity of Iowa Carver College of Medicine, Iowa City, Iowa.ORCID 0000-0002-9542-2454
Yuanyuan LiangDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0001-7409-3391
Shanshan LiMassMutual Data Science, Springfield, Massachusetts.
Daniel J DiekemaUniversity of Iowa Carver College of Medicine, Iowa City, Iowa.
Loreen A HerwaldtUniversity of Iowa Carver College of Medicine, Iowa City, Iowa.
J Kristie JohnsonDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.
Anthony D HarrisDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0003-2193-1560
Eli N PerencevichUniversity of Iowa Carver College of Medicine, Iowa City, Iowa.
University of Iowa · USUniversity of Maryland, Baltimore · USJohns Hopkins University · USUniversity of Arkansas for Medical Sciences · US

Funding

Institutional Career DevelopmentKL2TR003108 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI ARTHUR, JOHN M., BORSHEIM, ELISABET · 2019 to 2023
$2.3M
NCATS NIH HHS KL2 TR003108NCEZID CDC HHS U54 CK000450
6 · The paper itself

Abstract

objectiveThe gold standard for hand hygiene (HH) while wearing gloves requires removing gloves, performing HH, and donning new gloves between WHO moments. The novel strategy of applying alcohol-based hand rub (ABHR) directly to gloved hands might be effective and efficient.

designA mixed-method, multicenter, 3-arm, randomized trial.

settingAdult and pediatric medical-surgical, intermediate, and intensive care units at 4 hospitals.

participantsHealthcare personnel (HCP).

interventionsHCP were randomized to 3 groups: ABHR applied directly to gloved hands, the current standard, or usual care.

methodsGloved hands were sampled via direct imprint. Gold-standard and usual-care arms were compared with the ABHR intervention.

resultsBacteria were identified on gloved hands after 432 (67.4%) of 641 observations in the gold-standard arm versus 548 (82.8%) of 662 observations in the intervention arm (

conclusionsCompared with usual care, contamination of gloved hands was significantly reduced by applying ABHR directly to gloved hands but statistically higher than the gold standard. Given time savings and microbiological benefit over usual care and lack of feasibility of adhering to the gold standard, the Centers for Disease Control and Prevention and the World Health Organization should consider advising HCP to decontaminate gloved hands with ABHR when HH moments arise during single-patient encounters.

Indexed as

DecontaminationHand Hygiene2-PropanolAdultChildEthanolHandHand DisinfectionHealth PersonnelHumans2-PropanolEthanol

Identifiers

PMID37994538
PMCPMC11007359
OpenAlexW4388944520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.