ArticleInternational psychogeriatrics2024
Social connections as determinants of cognitive health and as targets for social interventions in persons with or at risk of Alzheimer's disease and related disorders: a scoping review.
Article in International psychogeriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Loneliness as an Interface Between Alzheimer's Disease and Suicidal Behaviour: A Systematic Review, Meta-Analysis and Meta-Analytic Factor Analysis.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026Pooled it
- Evidence-Based Pathways to Healthy Aging: A Systematic Review and Meta-analysis of Lifestyle Interventions for Longevity and Well-Being.Investigacion y educacion en enfermeria · 2025Pooled it
- Loneliness and cognition in older adults: A meta-analysis of harmonized studies from the United States, England, India, China, South Africa, Mexico, and Chile.Psychological medicine · 2025Pooled it
- Associations of Social Determinants of Health Scores with Visual Impairment and Premature Death in Visually Impaired Adults: Insights from CHARLS-A Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- Determinants of Dementia Risk Score in Primary Care: Knowledge Level, Social Factors, and Health Behaviours.Journal of prevention (2022) · 2026Article
- Association Between Relative Fat Mass and Risk of Cognitive Impairment: The Role of Social Determinants of Health.Actas espanolas de psiquiatria · 2026Article
- Gender differences in the influence of environmental hazards on dementia in older adults.The Gerontologist · 2026Article
- Feasibility of identifying factors related to Alzheimer's disease and related dementia in real-world data.JAMIA open · 2026Review
- Healthy lifestyle and Alzheimer's disease in individuals with hyperlipidemia: A prospective cohort study.The journal of prevention of Alzheimer's disease · 2026Article
- Older Adult Social Participation and Cognition: Illustrating Survey and Measurement Heterogeneity Across Studies.Research on aging · 2026Article
- Association of family and friend relationship satisfaction with incident dementia: A prospective cohort study of 104,093 participants.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Socio-emotional well-being is associated with cognitive function and informant-rated cognitive decline: Results from the Harmonized Cognitive Assessment Protocol in Europe.Journal of the International Neuropsychological Society : JINS · 2026Article
- The scope and impact of Walking the Talk for Dementia 2024.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Loneliness and cognitive decline among U.S. adults: A stratified analysis of the BRFSS.PloS one · 2026Article
- Prevention of cognitive decline and dementia: Current evidence on lifestyle factors and dietary patterns.EXCLI journal · 2026Review
- Current Perspectives on Oxytocin and Alzheimer's Disease-Related Symptoms.Current Alzheimer research · 2026Review
- Predictors and Correlates of Loneliness and Social Isolation in People With Dementia: Longitudinal Findings From the IDEAL Programme.International journal of geriatric psychiatry · 2026Article
- Synergistic effects of group-based exercise to reduce loneliness and social isolation and to prevent cognitive decline among older adults with cancer.Frontiers in aging · 2026Article
- Ability to Detect Digital Risks: Effects of an Educational Intervention and Dementia Risk Level.International journal of environmental research and public health · 2025Article
- Mapping social determinants of cognitive health in Canada: a scoping review.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 9 institutions in 1 country.
Funding
Abstract
backgroundSocial connections have a significant impact on health across age groups, including older adults. Loneliness and social isolation are known risk factors for Alzheimer's disease and related dementias (ADRD). Yet, we did not find a review focused on meta-analyses and systematic reviews of studies that had examined associations of social connections with cognitive decline and trials of technology-based and other social interventions to enhance social connections in people with ADRD. STUDY
designWe conducted a scoping review of 11 meta-analyses and systematic reviews of social connections as possible determinants of cognitive decline in older adults with or at risk of developing ADRD. We also examined eight systematic reviews of technology-based and other social interventions in persons with ADRD. STUDY
resultsThe strongest evidence for an association of social connections with lower risk of cognitive decline was related to social engagement and social activities. There was also evidence linking social network size to cognitive function or cognitive decline, but it was not consistently significant. A number of, though not all, studies reported a significant association of marital status with risk of ADRD. Surprisingly, evidence showing that social support reduces the risk of ADRD was weak. To varying degrees, technology-based and other social interventions designed to reduce loneliness in people with ADRD improved social connections and activities as well as quality of life but had no significant impact on cognition. We discuss strengths and limitations of the studies included.
conclusionsSocial engagement and social activities seem to be the most consistent components of social connections for improving cognitive health among individuals with or at risk for ADRD. Socially focused technology-based and other social interventions aid in improving social activities and connections and deserve more research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.