Evidence map›Paper›PMID 37993708›Full record

ArticleNature2023

Structural insights into intron catalysis and dynamics during splicing.

Ling Xu, Tianshuo Liu, Kevin Chung, Anna Marie Pyle

Abstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Controlled dynamic remodeling of the spliceosome active site enables the first step of splicing.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. RNA Triple Helices: From Structures and Mechanisms to Therapeutic Targets.International journal of biological sciences · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Molecular insights into de novo small-molecule recognition by an intron RNA structure.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ling Xu *Howard Hughes Medical Institute, Chevy Chase, MD, USA. ling.xu@yale.edu.ORCID 0000-0002-9057-0829
Tianshuo Liu *Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA.ORCID 0009-0006-7764-7402
Kevin Chung *Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.ORCID 0000-0003-0402-6833
Anna Marie PyleHoward Hughes Medical Institute, Chevy Chase, MD, USA. anna.pyle@yale.edu.ORCID 0000-0001-9045-8872

Funding

High-throughput electron cryo-microscopeS10OD023603 · OD · YALE UNIVERSITY · PI SIGWORTH, FREDERICK J · 2018 to 2018
$1.9M
NIH HHS S10 OD023603
6 · The paper itself

Abstract

The group II intron ribonucleoprotein is an archetypal splicing system with numerous mechanistic parallels to the spliceosome, including excision of lariat introns

Indexed as

BiocatalysisIntronsNucleic Acid ConformationRNA SplicingAdenosineCryoelectron MicroscopyExonsRNA PrecursorsRNA Splice SitesAdenosineRNA PrecursorsRNA Splice Sites

Identifiers

PMID37993708
PMCPMC10733145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.