Evidence map›Paper›PMID 37993551›Full record

ArticleAnalytical and bioanalytical chemistry2024

A novel SPE-LC-MRM strategy for serum demethylzeylasteral quantitation developed with an

Yi Wang, Ban Zhao, Xin Dang, Ling-Fei Kong, Yi-Cong Geng, Ping He, Zheng-Ying Li, Yong-Hui Mao, Cai Tie

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yi Wang *State Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources, Ding11 Xueyuan Road, Beijing, 100083, China.
Ban Zhao *Department of Nephrology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China.
Xin DangDepartment of Nephrology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China.
Ling-Fei KongState Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources, Ding11 Xueyuan Road, Beijing, 100083, China.
Yi-Cong GengState Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources, Ding11 Xueyuan Road, Beijing, 100083, China.
Ping HeState Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources, Ding11 Xueyuan Road, Beijing, 100083, China.
Zheng-Ying LiState Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources, Ding11 Xueyuan Road, Beijing, 100083, China.
Yong-Hui MaoDepartment of Nephrology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, China. maoyonghui0214@bjhmoh.cn.
Cai TieState Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources, Ding11 Xueyuan Road, Beijing, 100083, China. tiecai@cumtb.edu.cn.
China University of Mining and Technology · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Beijing Hospital 121 Project 121-2016008Fundamental Research Funds for the Central Universities No. 2023ZKPYHH05National Natural Science Foundation of China 81860727National Natural Science Foundation of China 81960752National Science and Technology Major Projects for "Major New Drugs Innovation and Development" 2017ZX09304026Open Fund of the State Key Laboratory Coal Resources and Safe Mining SKLCRSM21KFA11
6 · The paper itself

Abstract

Natural bioactive compounds (NBCs) are widely used in clinical treatment. For example, Tripterygium wilfordii Hook f. is commonly known in China as Lei-Gong-Teng which means thunder god vine. This herb is widely distributed in Eastern and Southern China, Korea, and Japan. The natural bioactive compounds of this herb can be extracted and made into tripterygium glycoside tablets. It is one of the most commonly used and effective traditional Chinese herbal medicines against rheumatoid arthritis (RA), nephrotic syndrome (NS), autoimmune hepatis (AIH), and so on. However, many NBCs are difficult to reliably quantify in the serum due to the effects of matrix and RSD. In addition, the targeted compound's internal standard (IS) is rarely sold due to the complex isotope internal standard synthesis pathway. In this study, a new quantitation method for

Indexed as

Arthritis, RheumatoidDrugs, Chinese HerbalTriterpenesGlycosidesHumansdemethylzeylasteralDrugs, Chinese HerbalGlycosidesTriterpenes16O/18O exchangingIsotopic labelingNatural bioactive compound quantitationSPEUPLC-MRM

Identifiers

PMID37993551
OpenAlexW4388932142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.