Evidence map›Paper›PMID 37993282›Full record

ArticleBMJ mental health2023

Relationship between self-stigma about alcohol dependence and severity of alcohol drinking and craving.

Madeline E Crozier, Mehdi Farokhnia, Susan Persky, Lorenzo Leggio, Brenda Curtis

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in BMJ mental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06676059 (SMART-r), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06676059 recruitingnot on this mapstarted 2026, after this paper: background citation

SMART-r: Substance Monitoring and Active Relapse Tracking Repository

TypeobservationalSponsorNational Institute on Drug Abuse (NIDA)Ran2026 to 2044Enrolled10,000ConditionsAlcoholism, Substance-Related Disorders
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Review
  3. The Association of Stigma and Alcohol Treatment Interest Among Women Veterans.Translational issues in psychological science · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Perceived stigma and its role in substance use disorder treatment completion.The American journal of drug and alcohol abuse · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Madeline E CrozierTranslational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA.
Mehdi FarokhniaTranslational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA.ORCID 0000-0003-0902-4212
Susan PerskySocial and Behavioral Research Branch, National Human Genome Research Institute Division of Intramural Research, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-7768-5744
Lorenzo LeggioTranslational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA.ORCID 0000-0001-7284-8754
Brenda CurtisTranslational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA brenda.curtis@nih.gov.ORCID 0000-0002-2511-3322
National Institutes of Health · US

Funding

Clinical Psychoneuroendocrinology and Neuropsychopharmacology (CPN)ZIADA000635 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LEGGIO, LORENZO · 2020 to 2025
$15.2M
Digital Markers in Relapse and RecoveryZIADA000628 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI CURTIS, BRENDA · 2019 to 2025
$10.0M
A Novel Compound for Alcoholism Treatment: a Translational StrategyUH3TR000963 · NCATS · UNIVERSITY OF RHODE ISLAND · PI AKHLAGHI, FATEMEH, LEGGIO, LORENZO · 2014 to 2016
$1.1M
A Novel Compound for Alcoholism Treatment: a Translational StrategyUH2TR000963 · NCATS · UNIVERSITY OF RHODE ISLAND · PI AKHLAGHI, FATEMEH, LEGGIO, LORENZO · 2013 to 2013
$550k
Intramural NIH HHS ZIA DA000628Intramural NIH HHS ZIA DA000635NCATS NIH HHS UH2 TR000963NCATS NIH HHS UH3 TR000963
6 · The paper itself

Abstract

backgroundThe correlates and consequences of stigma surrounding alcohol use are complex. Alcohol use disorder (AUD) is typically accompanied by self-stigma, due to numerous factors, such as shame, guilt and negative stereotypes. Few studies have empirically examined the possible association between self-stigma and alcohol-related outcomes.

objectiveTo investigate the relationship between self-stigma about alcohol dependence and the severity of alcohol consumption and craving.

methodsIn a sample of 64 participants, the majority of whom had a diagnosis of AUD (51), bivariate correlations were first conducted between Self-Stigma and Alcohol Dependence Scale (SSAD-Apply subscale) scores and Alcohol Use Disorders Identification Test (AUDIT) scores, Alcohol Timeline Follow-Back, Obsessive-Compulsive Drinking Scale (OCDS) scores and Penn Alcohol Cravings Scale scores. Based on the results, regression analyses were conducted with SSAD scores as the predictor and AUDIT and OCDS scores as the outcomes.

findingsSSAD scores positively correlated with AUDIT scores, average drinks per drinking day, number of heavy drinking days and OCDS scores (p<0.001, p=0.014, p=0.011 and p<0.001, respectively). SSAD scores were also found to be a significant predictor of AUDIT and OCDS scores (p<0.001 and p<0.001, respectively), even after controlling for demographics.

conclusionsHigher levels of self-stigma were associated with more severe AUD, greater alcohol consumption, and more obsessive thoughts and compulsive behaviours related to alcohol. CLINICAL IMPLICATIONS: Our results suggest that potential interventions to reduce self-stigma may lead to improved quality of life and treatment outcomes for individuals with AUD.

Indexed as

AlcoholismAlcohol DrinkingCompulsive BehaviorCravingHumansQuality of Lifesubstance misuse

Identifiers

PMID37993282
PMCPMC10668173
OpenAlexW4388923629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.