Evidence map›Paper›PMID 37993270›Full record

ArticleNeurology2023

Association of Whole Grain Consumption and Cognitive Decline: An Investigation From a Community-Based Biracial Cohort of Older Adults.

Xiaoran Liu, Todd Beck, Klodian Dhana, Pankaja Desai, Kristin R Krueger, Christy C Tangney, Thomas M Holland, Puja Agarwal, Denis A Evans, Kumar B Rajan

Abstract read
In one paragraph

Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Association of MIND diet with cognitive decline among Black and White older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaoran LiuFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL. xiaoran_liu@rush.edu.ORCID 0000-0001-7356-645X
Todd BeckFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.ORCID 0000-0001-8781-2105
Klodian DhanaFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.ORCID 0000-0002-6397-7009
Pankaja DesaiFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.ORCID 0000-0002-0904-5905
Kristin R KruegerFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.
Christy C TangneyFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.ORCID 0000-0002-2431-9687
Thomas M HollandFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.ORCID 0000-0002-9888-0194
Puja AgarwalFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.ORCID 0000-0002-0274-6653
Denis A EvansFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.ORCID 0000-0003-4755-5401
Kumar B RajanFrom the Rush Institute for Healthy Aging (X.L., T.B., K.D., P.D., K.R.K., T.M.H., D.A.E., K.B.R.), Rush University Medical Center; Department of Internal Medicine (X.L., T.B., K.D., P.D., K.R.K., T.M.H., P.A., D.A.E., K.B.R.), Rush University Medical Center; Department of Clinical Nutrition & Preventive Medicine (C.C.T.), Rush University Medical Center; and Rush Alzheimer's Disease Center (P.A.), Rush University Medical Center, Chicago, IL.

Funding

Impact of Neuroinflammation on AD Occurrence: A Bi-Generational Population StudyR01AG073627 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI NEELUM T. AGGARWAL, DENIS A EVANS · 2021 to 2026
$14.0M
Preserving Cognitive Resilience: A Biracial Parent-Offspring Study (18-4674) - Feasibility StudyR01AG058679 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI EVANS, DENIS A, RAJAN, KUMAR B. · 2019 to 2024
$13.8M
NIA NIH HHS R01 AG058679NIA NIH HHS R01 AG073627
6 · The paper itself

Abstract

BACKGROUND AND

objectivesTo examine the association of whole grain consumption and longitudinal change in global cognition, perceptual speed, and episodic memory by different race/ethnicity.

methodsWe included 3,326 participants from the Chicago Health and Aging Project who responded to a Food Frequency Questionnaire (FFQ), with 2 or more cognitive assessments. Global cognition was assessed using a composite score of episodic memory, perceptual speed, and the Mini Mental State Examination (MMSE). Diet was assessed by a 144-item FFQ. Linear mixed-effects models were used to estimate the association of intakes of whole grains and cognitive decline.

resultsThis study involved 3,326 participants (60.1% African American [AA], 63.7% female) with a mean age of 75 years at baseline and a mean follow-up of 6.1 years. Higher consumption of whole grains was associated with a slower rate of global cognitive decline. Among AA participants, those in the highest quintile of whole grain consumption had a slower rate of decline in global cognition (β = 0.024, 95% CI [0.008-0.039], DISCUSSION: Among AA participants, individuals with higher consumption of whole grains and more frequent consumption of whole grain had slower decline in global cognition, perceptual speed, and episodic memory. We did not see a similar trend in White adults.

Indexed as

Cognitive DysfunctionWhole GrainsAgedAgingCognitionDietFemaleHumansMale

Identifiers

PMID37993270
PMCPMC10727204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.