Evidence map›Paper›PMID 37992407›Full record

ArticleInternational journal of circumpolar health2023

Treatment of glioblastoma in Greenlandic patients.

Simone Frandsen, Alice Juhl Pedersen, Ole Gredal, Søren Møller, Uka Wilhjelm Geissler, Dorte Schou Nørøxe

Abstract read
In one paragraph

Article in International journal of circumpolar health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simone FrandsenDepartment of Medicine, Queen Ingrid's Hospital, Nuuk, Greenland.
Alice Juhl PedersenDepartment of Medicine, Queen Ingrid's Hospital, Nuuk, Greenland.
Ole GredalDepartment of Medicine, Queen Ingrid's Hospital, Nuuk, Greenland.
Søren MøllerDepartment of Oncology, Copenhagen University Hospital, Copenhagen, Denmark.
Uka Wilhjelm GeisslerDepartment of Medicine, Queen Ingrid's Hospital, Nuuk, Greenland.
Dorte Schou NørøxeDepartment of Medicine, Queen Ingrid's Hospital, Nuuk, Greenland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM), WHO grade IV, is the most common primary malignant brain tumour among adults with a devastating overall survival of 14-22 months. Standard treatment of GBM includes maximum safe resection, radiotherapy plus concomitant and adjuvant temozolomide (TMZ), given over a period of approximately 9 months. Treatment and follow-up for Greenlandic patients with GBM are managed at Rigshospitalet (RH), Copenhagen. Greenlandic GBM patients, therefore, travel back and forth to RH, often unaccompanied, and challenged by cognitive failure or other symptoms from their disease and/or treatment. Few Greenlandic patients are diagnosed with GBM annually, but considering the poor prognosis and short remaining lifespan, it would be preferable to limit their travels. TMZ is administrated as capsules. Health personnel at Queen Ingrid's Hospital (DIH), Nuuk, are trained in treating other oncological diseases and handling side effects. Hence, it could be investigated whether administration of adjuvant TMZ at DIH could be feasible after personnel education as well as economic consideration and compensation, in close collaboration with neuro oncologists at RH. In this article, we describe the Greenlandic cancer treatment, and the typical workflow from diagnosis of GBM to treatment to progression.

Indexed as

Brain NeoplasmsGlioblastomaAdultAntineoplastic Agents, AlkylatingChemotherapy, AdjuvantDacarbazineHumansTemozolomideAntineoplastic Agents, AlkylatingDacarbazineTemozolomidebrain cancerGlioblastomaGreenlandInuitradiotherapytemozolomide

Identifiers

PMID37992407
PMCPMC10997297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.