Evidence map›Paper›PMID 37992385›Full record

ArticleDermatology practical & conceptual2023

Monitoring of Vitiligo Patches Over Six Months to Validate Dermoscopic Findings of Lesional Stability.

Chitra Kamath, Rachita Dhurat, Bhavika Shah, Richa Sharma, Priyanka Arun Kowe, Sachin Chamle

Open access · diamondAbstract read
In one paragraph

Article in Dermatology practical & conceptual, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chitra KamathDepartment of Dermatology, Venerology and Leprosy, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.
Rachita DhuratDepartment of Dermatology, Venerology and Leprosy, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.
Bhavika ShahDepartment of Dermatology, Venerology and Leprosy, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.
Richa SharmaDepartment of Dermatology, Venerology and Leprosy, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.
Priyanka Arun KoweDepartment of Dermatology, Venerology and Leprosy, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.
Sachin ChamleDepartment of Dermatology, Venerology and Leprosy, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.
Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPreviously laid down criteria for lesional stability of vitiligo are inconsistent. Longitudinal data on correlation between dermoscopic features of vitiligo and disease activity is limited.

objectivesTo sequentially determine the dermoscopic features of vitiligo and to assess their association with the dynamic nature of the vitiligo patch.

methodsSixty patients with 200 vitiligo patches fulfilling the inclusion criteria on medical therapy were subjected to sequential clinical and dermoscopic examination for 6 months. Baseline lesional photographs, dermoscopy and tracing of the patch was made and repeated at 6 months. The follow up tracing was superimposed onto the baseline tracing. Based on the increase or decrease in size, their outcomes were grouped as responsive, progressive and quiescent. Paired analysis of dermoscopic features was done between baseline, and their follow up after 6 months.

resultsWell defined border was associated with static nature of the vitiligo patch and ill-defined borders and trichrome pattern depicted its dynamic nature. Statistically significant increase in leukotrichia and satellite lesions amongst progressive patches and a decrease amongst responsive patches was observed. Pigment network changes were statistically significant for both responsive and progressive patches. Satellite lesions and micro-Koebner's phenomena was suggestive of progressive disease, while perifollicular pigmentation and perilesional hyperpigmentation was suggestive of re-pigmenting disease and proved to be an early marker for response to therapy.

conclusionsRepeated dermoscopic evaluation of lesions in a serial manner to assess disease activity helps understand their evolving nature and is a valuable tool in planning appropriate further treatment.

Identifiers

PMID37992385
PMCPMC10656188
OpenAlexW4388075247

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.