Evidence map›Paper›PMID 37992184›Full record

ArticleThe Journal of bone and joint surgery. American volume2024

Hip Morphology on Post-Reduction MRI Predicts Residual Dysplasia 10 Years After Open or Closed Reduction.

Florian Schmaranzer, Pedro Justo, Jennifer R Kallini, Mariana G Ferrer, Patricia Miller, Sarah D Bixby, Eduardo N Novais

Open access · greenAbstract read
In one paragraph

Article in The Journal of bone and joint surgery. American volume, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Florian SchmaranzerDepartment of Diagnostic, Interventional, and Pediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-8729-7243
Pedro JustoChild and Young Adult Hip Preservation Program, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0003-3773-3155
Jennifer R KalliniChild and Young Adult Hip Preservation Program, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0001-7785-1696
Mariana G FerrerChild and Young Adult Hip Preservation Program, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0002-0969-2424
Patricia MillerChild and Young Adult Hip Preservation Program, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0002-0141-717
Sarah D BixbyDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0002-6271-6085
Eduardo N NovaisChild and Young Adult Hip Preservation Program, Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0002-9187-3100
Boston Children's Hospital · USUniversity of Bern · CH

Funding

Regenerative Musculoskeletal Medicine Training ProgramT32AR059033 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI John S Adams, Nicholas M. Bernthal · 2011 to 2026
$4.8M
NIAMS NIH HHS T32 AR059033
6 · The paper itself

Abstract

backgroundThere is limited evidence supporting the value of morphological parameters on post-reduction magnetic resonance imaging (MRI) to predict long-term residual acetabular dysplasia (RAD) after closed or open reduction for the treatment of developmental dysplasia of the hip (DDH).

methodsWe performed a retrospective study of 42 patients (47 hips) undergoing open or closed reduction with a minimum 10 years of follow-up; 39 (83%) of the hips were in female patients, and the median age at reduction was 6.3 months (interquartile range [IQR], 3.3 to 8.9 months). RAD was defined as additional surgery with an acetabular index >2 standard deviations above the age- and sex-specific population-based mean value or Severin classification grade of >2 at last follow-up. Acetabular version and depth-width ratio, coronal and axial femoroacetabular distance, cartilaginous and osseous acetabular indices, transverse ligament thickness, and the thickness of the medial and lateral (limbus) acetabular cartilage were measured on post-reduction MRI.

resultsAt the time of final follow-up, 24 (51%) of the hips had no RAD; 23 (49%) reached a failure end point at a median of 11.4 years (IQR, 7.6 to 15.4 years). Most post-reduction MRI measurements, with the exception of the cartilaginous acetabular index, revealed a significant distinction between the group with RAD and the group with no RAD when mean values were compared. The coronal femoroacetabular distance (area under the receiver operating characteristic curve [AUC], 0.95; 95% confidence interval [CI], 0.90 to 1.00), with a 5-mm cutoff, and limbus thickness (AUC, 0.91; 95% CI, 0.83 to 0.99), with a 4-mm cutoff, had the highest discriminatory ability. A 5-mm cutoff for the coronal femoroacetabular distance produced 96% sensitivity (95% CI, 78% to 100%), 83% specificity (95% CI, 63% to 95%), 85% positive predictive value (95% CI, 65% to 96%), and 95% negative predictive value (95% CI, 76% to 100%). A 4-mm cutoff for limbus thickness had 96% sensitivity (95% CI, 78% to 100%), 63% specificity (95% CI, 41% to 81%), 71% positive predictive value (95% CI, 52% to 86%), and 94% negative predictive value (95% CI, 70% to 100%).

conclusionsCoronal femoroacetabular distance, a quantitative metric assessing a reduction's concentricity, and limbus thickness, a quantitative metric assessing the acetabulum's cartilaginous component, help to predict hips that will have RAD in the long term after closed or open reduction. LEVEL OF EVIDENCE: Diagnostic Level IV . See Instructions for Authors for a complete description of levels of evidence.

Indexed as

Hip DislocationHip Dislocation, CongenitalAcetabulumCartilageFemaleHip JointHumansInfantMagnetic Resonance ImagingMaleRetrospective StudiesTreatment Outcome

Identifiers

PMID37992184
PMCPMC12205695
OpenAlexW4388901974

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.