Evidence map›Paper›PMID 37992076›Full record

SynthesisPloS one2023

Cardiometabolic risk factors in South American children: A systematic review and meta-analysis.

Carolyn M H Singleton, Sumeer Brar, Nicole Robertson, Lauren DiTommaso, George J Fuchs, Aric Schadler, Aurelia Radulescu, Suzanna L Attia

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carolyn M H SingletonUniversity of Kentucky College of Medicine, Lexington, Kentucky, United States of America.ORCID 0000-0001-9874-9025
Sumeer BrarUniversity of Kentucky College of Medicine, Lexington, Kentucky, United States of America.
Nicole RobertsonUniversity of Kentucky College of Medicine, Lexington, Kentucky, United States of America.
Lauren DiTommasoUniversity of Kentucky College of Medicine, Lexington, Kentucky, United States of America.
George J FuchsUniversity of Kentucky College of Medicine Division of Pediatric Gastroenterology, Hepatology and Nutrition, Kentucky, United States of America.
Aric SchadlerUniversity of Kentucky College of Medicine Department of Pediatrics, Kentucky, United States of America.
Aurelia RadulescuUniversity of Kentucky College of Medicine Department of Pediatrics, Kentucky, United States of America.
Suzanna L AttiaUniversity of Kentucky College of Medicine Division of Pediatric Gastroenterology, Hepatology and Nutrition, Kentucky, United States of America.ORCID 0000-0002-2689-3340

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiometabolic risk factors (impaired fasting glucose, abdominal obesity, high blood pressure, dyslipidemia) cluster in children, may predict adult disease burden, and are inadequately characterized in South American children.

objectivesTo quantify the burden of cardiometabolic risk factors in South American children (0-21 years) and identify knowledge gaps.

methodsWe systematically searched PubMed, Google Scholar, and the Latin American and Caribbean Health Sciences Literature via Virtual Health Library from 2000-2021 in any language. Two independent reviewers screened and extracted all data.

results179 studies of 2,181 screened were included representing 10 countries (n = 2,975,261). 12.2% of South American children experienced obesity, 21.9% elevated waist circumference, 3.0% elevated fasting glucose, 18.1% high triglycerides, 29.6% low HDL cholesterol, and 8.6% high blood pressure. Cardiometabolic risk factor definitions varied widely. Chile exhibited the highest prevalence of obesity/overweight, low HDL, and impaired fasting glucose. Ecuador exhibited the highest prevalence of elevated blood pressure. Rural setting (vs. urban or mixed) and indigenous origin protected against most cardiometabolic risk factors.

conclusionsSouth American children experience high rates of obesity, overweight, and dyslipidemia. International consensus on cardiometabolic risk factor definitions for children will lead to improved diagnosis of cardiometabolic risk factors in this population, and future research should ensure inclusion of unreported countries and increased representation of indigenous populations.

Indexed as

Cardiovascular DiseasesDyslipidemiasHypertensionAdultBlood GlucoseBody Mass IndexCardiometabolic Risk FactorsChildChileHumansObesityOverweightRisk FactorsWaist CircumferenceBlood Glucose

Identifiers

PMID37992076
PMCPMC10664905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.