Evidence map›Paper›PMID 37992063›Full record

ArticlePloS one2023

Improving care engagement for mobile people living with HIV in rural western Kenya.

James Ayieko, Edwin D Charlebois, Irene Maeri, Lawrence Owino, Marguerite Thorp, Elizabeth A Bukusi, Maya L Petersen, Moses R Kamya, Diane V Havlir, Carol S Camlin

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01864603 (Sustainable East Africa Research in Community Health), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01864603 nacompletednot on this map

Sustainable East Africa Research in Community Health

TypeinterventionalSponsorUniversity of California, San FranciscoRan2013 to 2021Enrolled150,395ConditionsHIV, Tuberculosis, Hypertension, DiabetesArmsUniversal ART in a streamlined care model, Annual Community Health Campaigns, Targeted PrEP and Targeted testing interventions, Baseline community-based HIV and multi-disease testing
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

James AyiekoCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.ORCID 0000-0002-0324-4006
Edwin D CharleboisDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Irene MaeriCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Lawrence OwinoCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.ORCID 0000-0002-3817-4386
Marguerite ThorpDepartment of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.
Elizabeth A BukusiCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Maya L PetersenSchool of Public Health, University of California Berkeley, Berkeley, California, United States of America.
Moses R KamyaInfectious Diseases Research Collaboration, Kampala, Uganda.
Diane V HavlirDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Carol S CamlinDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East AfricaU01AI150510 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAVLIR, DIANE V, KAMYA, MOSES ROBERT · 2020 to 2025
$23.4M
University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
Understanding mobility and risk in SEARCH communitiesR01MH104132 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CAMLIN, CAROL SUZANNE · 2015 to 2019
$3.1M
Mentoring Clinical Investigators in Patient Oriented Research on Human Mobility and HIVK24MH126808 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CAMLIN, CAROL SUZANNE · 2021 to 2025
$827k
FIC NIH HHS D43 TW009343NIAID NIH HHS U01 AI150510NIMH NIH HHS K24 MH126808NIMH NIH HHS P30 MH062246NIMH NIH HHS R01 MH104132
6 · The paper itself

Abstract

backgroundAntiretroviral therapy (ART) assures major gains in health outcomes among people living with HIV, however, this benefit may not be realized by all due to care interruptions. Mobile populations comprise a subgroup that is likely to have sub-optimal care engagement, resulting in discontinuation of ART. We sought to evaluate the barriers to care engagement among highly mobile individuals living with HIV and explore options aimed at improving engagement in care for this group.

methodsQualitative in-depth interviews were conducted in 2020 among a purposive sample of twelve persons living with HIV and eight health care providers in western Kenya, within a mixed methods study of mobility in communities participating in the SEARCH trial (NCT01864603). We explored the barriers to care engagement among mobile individuals living with HIV and explored different options aimed at enhancing care engagement. These included options such as a coded card containing treatment details, alternative drug packaging to conceal drug identity, longer refills to cover travel period, wrist bands with data storage capability to enable data transfer and "warm handoff" by providers to new clinics upon transfer. Data were inductively analyzed to understand the barriers and acceptability of potential interventions to address them.

resultsStigma and lack of disclosure, rigid work schedules, and unpredictability of travel were major barriers to care engagement for highly mobile individuals living with HIV. Additionally, lack of flexibility in clinic schedules and poor provider attitude were identified as health-system-associated barriers to care engagement. Options that enhance flexibility, convenience and access to care were viewed as the most effective means of addressing the barriers to care by both patients and providers. The most preferred option was a coded card with treatment details followed by alternative drug packaging to conceal drug identity due to stigma and longer refills to cover travel periods.

conclusionHighly mobile individuals living with HIV desire responsive, flexible, convenient and patient-centered care delivery models to enhance care engagement. They embraced simple health delivery improvements such as coded cards, alternative drug packaging and longer refills to address challenges of mobility.

Indexed as

Anti-HIV AgentsHIV InfectionsHumansKenyaQualitative ResearchQuality ImprovementAnti-HIV Agents

Identifiers

PMID37992063
PMCPMC10664942

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.