Observational studyPloS one2023
Associations of SARS-CoV-2 antibodies with birth outcomes: Results from three urban birth cohorts in the NIH environmental influences on child health outcomes program.
Leonardo Trasande, Sarah S Comstock, Julie B Herbstman, Amy Margolis, Garry Alcedo, Yelena Afanasyeva, Keunhyung Yu, William Lee, David A Lawrence, program collaborators for Environmental influences on Child Health Outcomes
Open access · goldAbstract readObservational Study
In one paragraphObservational study in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors at 6 institutions in 1 country.
Leonardo TrasandeDivision of Environmental Pediatrics, Department of Pediatrics, NYU Grossman School of Medicine, New York, NY, United States of America.ORCID 0000-0002-1928-597X Sarah S ComstockDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States of America.
Julie B HerbstmanDepartment of Environmental Health Sciences, Columbia Mailman School of Public Health, New York, NY, United States of America.
Amy MargolisDepartment of Psychiatry, Columbia University Medical Center, New York, NY, United States of America.
Garry AlcedoDivision of Environmental Pediatrics, Department of Pediatrics, NYU Grossman School of Medicine, New York, NY, United States of America.
Yelena AfanasyevaDivision of Environmental Pediatrics, Department of Pediatrics, NYU Grossman School of Medicine, New York, NY, United States of America.
Keunhyung YuDivision of Environmental Pediatrics, Department of Pediatrics, NYU Grossman School of Medicine, New York, NY, United States of America.
William LeeWadsworth Laboratories, New York State Department of Health, Albany, NY, United States of America.
David A LawrenceWadsworth Laboratories, New York State Department of Health, Albany, NY, United States of America.
program collaborators for Environmental influences on Child Health Outcomes
New York University · USNew York State Department of Health · USColumbia University · USColumbia University Irving Medical Center · USMichigan State University · USWagner College · US
Funding
Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Linda S Adair, Phillip Brian Smith · 2016 to 2026
$215.9MECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4MWisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUH3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern · 2018 to 2026
$64.8MThe NYU Children’s Health & Environment Study: an ECHO CohortUH3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian, Leonardo Trasande · 2018 to 2026
$59.5MThe ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7MUnderstanding Breastfeeding Practices Among ECHO Cohort Participants Before and During/After the COVID-19 PandemicUH3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI Charles James Barone, MICHAEL R. ELLIOTT · 2018 to 2026
$24.5MWisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUG3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI GERN, JAMES E. · 2016 to 2024
$19.3MNot whether but how: The ethics of reporting individual results in a pregnancy cohort.UH3OD023290 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Julie Beth Herbstman, AMY MARGOLIS · 2018 to 2026
$18.8MNIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UG3 OD023282NIH HHS UH3 OD023282NIH HHS UH3 OD023285NIH HHS UH3 OD023290NIH HHS UH3 OD023305
6 · The paper itselfAbstract
Studies suggest perinatal infection with SARS-CoV-2 can induce adverse birth outcomes, but studies published to date have substantial limitations. We therefore conducted an observational study of 211 births occurring between January 2020-September 2021 in three urban cohorts participating in the Environmental Influences on Child Health Outcomes Program. Serology was assessed for IgG, IgM and IgA antibodies to nucleocapsid, S1 spike, S2 spike, and receptor-binding domain. There were no differences in gestational age (GA), birth weight, preterm birth (PTB) or low birth weight (LBW) among seropositive mothers. However, the few (n = 9) IgM seropositive mothers had children with lower BW (434g, 95% CI: 116-752), BW Z score-for-GA (0.73 SD, 95% CI 0.10-1.36) and were more likely to deliver preterm (OR 8.75, 95% CI 1.22-62.4). Though there are limits to interpretation, the data support efforts to prevent SARS-CoV-2 infections in pregnancy.
Indexed as
COVID-19Premature BirthBirth CohortChildFemaleHumansImmunoglobulin MInfant, NewbornOutcome Assessment, Health CarePregnancySARS-CoV-2Immunoglobulin M
Identifiers
PMID37992059
PMCPMC10664934
OpenAlexW4388894705
What OpenQuestion holds
Textmetadata
LicenceCC BY
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