Evidence map›Paper›PMID 37991761›Full record

Trial reportJAMA network open2023

Catheter Ablation With Morphologic Repetitiveness Mapping for Persistent Atrial Fibrillation.

Chin-Yu Lin, Yenn-Jiang Lin, Satoshi Higa, Wen-Chin Tsai, Men-Tzung Lo, Chia-Hsin Chiang, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Tze-Fan Chao and 15 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in JAMA network open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05333952 (A Randomized Controlled Study on the Waveform Periodicity Analysis of Complex Fractionated Electrograms in Patients With Persistent Atrial Fibrillation), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05333952 naunknown statusnot on this map

A Randomized Controlled Study on the Waveform Periodicity Analysis of Complex Fractionated Electrograms in Patients With Persistent Atrial Fibrillation

TypeinterventionalSponsorTaipei Veterans General Hospital, TaiwanRan2019 to 2025Enrolled80ConditionsAtrial Fibrillation, PersistentArmsPulmonary vein isolation, Substrate ablation(PRISM based)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Navigating the Ebb and Flow of Atrial Fibrillation.JACC. Clinical electrophysiology · 2024
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 8 institutions in 2 countries.

Chin-Yu LinMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Yenn-Jiang LinMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Satoshi HigaCardiac Electrophysiology and Pacing Laboratory, Division of Cardiovascular Medicine, Makiminato Central Hospital, Okinawa, Japan.
Wen-Chin TsaiDivision of Cardiology, Tzu-Chi General Hospital, Institute of Medical Sciences, Tzu-Chi University, Hualien, Taiwan.
Men-Tzung LoDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.
Chia-Hsin ChiangDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.
Shih-Lin ChangMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Li-Wei LoMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Yu-Feng HuMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Tze-Fan ChaoMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Fa-Po ChungMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Jo-Nan LiaoMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Ting-Yung ChangMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Chen LinCardiac Electrophysiology and Pacing Laboratory, Division of Cardiovascular Medicine, Makiminato Central Hospital, Okinawa, Japan.
Ta-Chuan TuanMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Ling KuoMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Cheng-I WuMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Chih-Min LiuMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Shin-Huei LiuMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Ming-Jen KuoMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Ying-Chieh LiaoDivision of Cardiovascular Medicine, Changhua Christian Hospital, Changhua City, Taiwan.
Chieh-Mao ChuangCardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.
Yun-Yu ChenHeart Rhythm Center, Taipei Veterans General Hospital, Taipei, Taiwan.
Yu-Cheng HsiehMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Shih-Ann ChenMedicine and Institute of Clinical Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan.
Taipei Veterans General Hospital · TWNational Yang Ming Chiao Tung University · TWNational Central University · TWChanghua Christian Hospital · TWNational Chung Hsing University · TWTaichung Veterans General Hospital · TWTomishiro Central Hospital · JPTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Catheter ablation for persistent atrial fibrillation (AF) has shown limited success. Objective: To determine whether AF drivers could be accurately identified by periodicity and similarity (PRISM) mapping ablation results for persistent AF when added to pulmonary vein isolation (PVI). Design, Setting, and Participants: This prospective randomized clinical trial was performed between June 1, 2019, and December 31, 2020, and included patients with persistent AF enrolled in 3 centers across Asia. Data were analyzed on October 1, 2022. Intervention: Patients were assigned to the PRISM-guided approach (group 1) or the conventional approach (group 2) at a 1:1 ratio. Main Outcomes and Measures: The primary outcome was freedom from AF or other atrial arrhythmia for longer than 30 seconds at 6 and 12 months. Results: A total of 170 patients (mean [SD] age, 62.0 [12.3] years; 136 men [80.0%]) were enrolled (85 patients in group 1 and 85 patients in group 2). More group 1 patients achieved freedom from AF at 12 months compared with group 2 patients (60 [70.6%] vs 40 [47.1%]). Multivariate analysis indicated that the PRISM-guided approach was associated with freedom from the recurrence of atrial arrhythmia (hazard ratio, 0.53 [95% CI, 0.33-0.85]). Conclusions and Relevance: The waveform similarity and recurrence pattern derived from high-density mapping might provide an improved guiding approach for ablation of persistent AF. Compared with the conventional procedure, this novel specific substrate ablation strategy reduced the frequency of recurrent AF and increased the likelihood of maintenance of sinus rhythm. Trial Registration: ClinicalTrials.gov Identifier: NCT05333952.

Indexed as

Atrial FibrillationCatheter AblationAsiaHumansMaleMiddle AgedMultivariate AnalysisProspective Studies

Identifiers

PMID37991761
PMCPMC10665974
OpenAlexW4388896029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.