ArticleBiological trace element research2024
Effects of Dietary Selenium Yeast Supplementation on Oxidative Biomarkers of the Brain and Blood in Goats.
Article in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Synergistic regulation of selenium yeast and vitamin E on the rumen microbiota-VFA-liver axis in lambs.BMC microbiology · 2026Article
- A Comprehensive Review of Selenium as a Key Regulator in Thyroid Health.Biological trace element research · 2025Review
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Authors and funding
3 authors at 2 institutions in 2 countries.
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Abstract
The present study evaluated the effects of dietary selenium yeast (SY) on the brain, CSF, and blood of 30 crossbreed goats (5-6 months of age) of both sexes. After the acclimatization of 2 weeks, they were randomly separated into two groups (n = 15) named C and SY groups. The C group received only a basal diet, while SY received a basal diet along with 0.3 mg/kg/diet of SY (Sel-Plex®) in total 0.035 mg/kg/diet of SY for 10 weeks. Se concentration (µg /g dry weight) in 15 different parts of the goat's brain was accessed, and results showed that the highest concentration was found in the occipital cerebrum (322.0 ± 6.146), whereas the lowest concentration was found in the midbrain (10.33 ± 0.232). Besides, the oxidative biomarkers including GSH (12.13 ± 0.191), GSH-Px (206.7 ± 2.362), GST (23.80 ± 0.279), CAT (14.80 ± 0.279), and SOD (152.5 ± 9.540) were increased in SY as compared to GSH (8.200 ± 0.144), GSH-Px (112.9 ± 1.183), GST (18.93 ± 0.284), CAT (12.53 ± 0.215), and SOD (109.0 ± 1.966) of C. The level of cholesterol was also significantly decreased in the serum of the SY group (84.87 ± 0.960) as compared to C (110.5 ± 0.592). In addition, the cholesterol level in CSF decreased significantly in SY (0.3567 ± 0.016) as compared to C (0.509 ± 0.009). The current research suggests that SY supplementation has improved the brain's antioxidant status, blood biochemistry, and cholesterol levels in both serum and CSF of goats.
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