ReviewJournal of experimental orthopaedics2023
Definitions and consequences of current alignment techniques and phenotypes in total knee arthroplasty (TKA) - there is no winner yet.
Review in Journal of experimental orthopaedics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- High variability exists in 3D leg alignment analysis, but underlying principles that might lead to agreement on a universal framework could be identified: A systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Pooled it
- Coronal plane alignment of the knee (CPAK) phenotypes and their relationship with gap patterns in robotic-assisted total knee arthroplasty: a clinical trial.Orthopadie (Heidelberg, Germany) · 2026Trial
- Improved accuracy of functional alignment restoration with robotic-assisted total knee arthroplasty : A quasi-randomized controlled trial.Orthopadie (Heidelberg, Germany) · 2026Trial
- The three-pillar concept for functional knee positioning in robotic total knee arthroplasty.Journal of experimental orthopaedics · 2026Review
- Mechanically aligned total knee arthroplasty demonstrates acceptable outcomes in obese patients, with insufficient evidence for alternative alignment strategies: A systematic review.Journal of experimental orthopaedics · 2026Review
- Radiolucent lines after robotic-assisted surface-matching kinematically aligned UKA: short-term incidence and lack of association with tibial alignment.Archives of orthopaedic and trauma surgery · 2026Article
- Patient-Specific Restoration of Constitutional Alignment Within Predefined Safety Boundaries Using Three-Dimensional Navigation in Primary Total Knee Arthroplasty: One-Year Clinical and Radiographic Outcomes.Journal of clinical medicine · 2026Article
- Impact of Antibiotic Bone Cement on Infection Rates in Primary Total Knee Arthroplasty: A GRADE-Assessed Systematic Review and Meta-Analysis of Observational Studies Involving Over 4 Million Patients.Open forum infectious diseases · 2026Review
- Sex-specific patterns and limited bilateral symmetry in coronal knee alignment: Insights from the modified coronal plane alignment of the knee classification.Osteoarthritis and cartilage open · 2026Article
- Does surgeon handedness affect the outcomes after primary total knee arthroplasty? A retrospective cohort study.World journal of orthopedics · 2026Article
- Functional alignment preserves the native Coronal Plane Alignment of the Knee phenotype while improving early clinical outcomes after robotic-assisted total knee arthroplasty.Orthopedic reviews · 2026Article
- Sex-specific differences in coronal knee alignment and CPAK distribution in an Austrian population.Archives of orthopaedic and trauma surgery · 2025Article
- Functional alignment in robotic total knee arthroplasty achieves comparable outcomes in varus and valgus knees despite distinct intraoperative strategies: Analysis of 355 consecutive cases.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- Mechanical Versus Restrictive Kinematic Alignment in Robotic-Assisted Total Knee Arthroplasty: A Randomized Controlled Trial.Diagnostics (Basel, Switzerland) · 2025Article
- The P Balasubramaniam Award-2024 Singapore Orthopaedic Association Annual Scientific Meeting Award: Novel artificial intelligence algorithm for soft tissue balancing and bone cuts in robotic total knee arthroplasty improves accuracy and surgical durationArthroplasty (London, England) · 2025Article
- Phenotyping the knee joint-A critical appraisal of CPAK for alignment classification.Journal of experimental orthopaedics · 2025Article
- The impact of total knee arthroplasty on functional outcomes and mental health: A prospective study.Journal of experimental orthopaedics · 2025Article
- Robotic total knee arthroplasty for moderate to high-grade valgus knee deformity: technique and outcomes.SICOT-J · 2025Article
- Article
- Custom total knee arthroplasty with personalised alignment showed better 2-year functional outcome compared to off-the-shelf arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dissatisfaction following total knee arthroplasty (TKA) has been extensively documented and it was attributed to numerous factors. In recent years, significant focus has been directed towards implant alignment and stability as potential causes and solutions to this issue. Surgeons are now exploring a more personalized approach to TKA, recognizing the importance of thoroughly understanding each individual patient's anatomy and functional morphology. A more comprehensive preoperative analysis of alignment and knee morphology is essential to address the unresolved questions in knee arthroplasty effectively. The crucial task of determining the most appropriate alignment strategy for each patient arises, given the substantial variability in bone resection resulting from the interplay of phenotype and the alignment strategy chosen. This review aims to comprehensively present the definitions of different alignment techniques in all planes and discuss the consequences dependent on knee phenotypes.Level of evidence V.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.