Evidence map›Paper›PMID 37991554›Full record

ArticleSkeletal radiology2024

Whole-body MRI for the investigation of joint involvement in inflammatory arthritis.

Jane Freeston, Matthew Marzetti, Neal Larkman, Emma Rowbotham, Paul Emery, Andrew Grainger

Open access · hybridAbstract read
In one paragraph

Article in Skeletal radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Whole-body MRI in arthritis.Skeletal radiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jane FreestonLeeds NIHR Musculoskeletal Biomedical Research Centre, Leeds, UK.
Matthew MarzettiLeeds NIHR Musculoskeletal Biomedical Research Centre, Leeds, UK. m.marzetti@nhs.net.ORCID http://orcid.org/0000-0001-9782-6383
Neal LarkmanDepartment of Radiology, Harrogate and District NHS Foundation Trust, Harrogate, UK.
Emma RowbothamLeeds NIHR Musculoskeletal Biomedical Research Centre, Leeds, UK.
Paul EmeryLeeds NIHR Musculoskeletal Biomedical Research Centre, Leeds, UK.
Andrew GraingerDepartment of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Leeds Teaching Hospitals NHS Trust · GBUniversity of Leeds · GBCambridge University Hospitals NHS Foundation Trust · GBHarrogate and District NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to develop a novel whole-body MRI protocol capable of assessing inflammatory arthritis at an early stage in multiple joints in one examination. MATERIALS AND

methodsForty-six patients with inflammatory joint symptoms and 9 healthy volunteers underwent whole-body MR imaging on a 3.0 T MRI scanner in this prospective study. Image quality and pathology in each joint, bursae, entheses and tendons were scored by two of three radiologists and compared to clinical joint scores. Participants were divided into three groups based on diagnosis at 1-year follow-up (healthy volunteers, rheumatoid arthritis and all other types of arthritis). Radiology scores were compared between the three groups using a Kruskal-Wallis test. The clinical utility of radiology scoring was compared to clinical scoring using ROC analysis.

resultsA protocol capable of whole-body MR imaging of the joints with an image acquisition time under 20 min was developed with excellent image quality. Synovitis scores were significantly higher in patients who were diagnosed with rheumatoid arthritis at 12 months (p < 0.05). Radiology scoring of bursitis showed statistically significant differences between each of the three groups-healthy control, rheumatoid arthritis and non-rheumatoid arthritis (p < 0.05). There was no statistically significant difference in ROC analysis between MRI and clinical scores.

conclusionThis study has developed a whole-body MRI joint imaging protocol that is clinically feasible and shows good differentiation of joint pathology between healthy controls, patients with rheumatoid arthritis and patients with other forms of arthritis.

Indexed as

Arthritis, RheumatoidSynovitisHumansMagnetic Resonance ImagingProspective StudiesROC CurveWrist JointWhole-body MR imaging, Magnetic resonance imaging, Inflammatory arthritis

Identifiers

PMID37991554
PMCPMC10972907
OpenAlexW4388900978

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.