Evidence map›Paper›PMID 37991280›Full record

ArticleJournal of computational chemistry2024

Spontaneous curvature generation by peptides in asymmetric bilayers.

Soohyung Park, Amy Rice, Wonpil Im, Richard W Pastor

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of computational chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A unified model of transient poration induced by antimicrobial peptides.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Soohyung ParkDepartments of Biological Sciences and Chemistry, Lehigh University, Bethlehem, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-4883-3031
Amy RiceLaboratory of Computational Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-7816-8650
Wonpil ImDepartments of Biological Sciences and Chemistry, Lehigh University, Bethlehem, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-5642-6041
Richard W PastorLaboratory of Computational Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-2454-5131

Funding

Computer Simulations of Membranes and BiopolymersZIAHL000340 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI PASTOR, RICHARD WALTER · 2009 to 2025
$29.1M
Computer Simulations of Membranes and BiopolymersZ01HL000340 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI PASTOR, RICHARD WALTER · 2006 to 2008
$2.9M
Intramural NIH HHS Z01 HL000340Intramural NIH HHS Z99 HL999999NIH HHS
6 · The paper itself

Abstract

Peptides and proteins play crucial roles in membrane remodeling by inducing spontaneous curvature. However, extracting spontaneous curvatures from simulations of asymmetric bilayers is challenging because differential stress (i.e., the difference of the leaflet surface tensions) arising from leaflet area strains can vary substantially among initial conditions. This study investigates peptide-induced spontaneous curvature

Indexed as

Lipid BilayersMolecular Dynamics SimulationPeptidesLipid BilayersPeptidesasymmetric bilayerschemical potentialdifferential stressP21 periodic boundary conditionspeptidesspontaneous curvature

Identifiers

PMID37991280
PMCPMC10922693

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.