ArticleInternational journal for numerical methods in biomedical engineering2024
The ocular mathematical virtual simulator: A validated multiscale model for hemodynamics and biomechanics in the human eye.
Article in International journal for numerical methods in biomedical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Comparing Interface Conditions for a 3D-0D Multiscale Interface Coupling With Applications in Tissue Perfusion.International journal for numerical methods in biomedical engineering · 2025Article
- Analysis of Waveform Parameters in the Retinal VasculatureLa matematica · 2024Article
- Impact of Elevated Intraocular Pressure on Lamina Cribrosa Oxygenation: A Combined Experimental-Computational Study on Monkeys.Ophthalmology scienceArticle
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Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
Abstract
We present our continuous efforts from a modeling and numerical viewpoint to develop a powerful and flexible mathematical and computational framework called Ocular Mathematical Virtual Simulator (OMVS). The OMVS aims to solve problems arising in biomechanics and hemodynamics within the human eye. We discuss our contribution towards improving the reliability and reproducibility of computational studies by performing a thorough validation of the numerical predictions against experimental data. The OMVS proved capable of simulating complex multiphysics and multiscale scenarios motivated by the study of glaucoma. Furthermore, its modular design allows the continuous integration of new models and methods as the research moves forward, and supports the utilization of the OMVS as a promising non-invasive clinical investigation tool for personalized research in ophthalmology.
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