Evidence map›Paper›PMID 37990733›Full record

Article3 Biotech2023

Evaluation of gut microbiota composition to screening for potential biomarker in AFB1-exposed sheep.

Luxi Lin, Pengfei Fu, Chaodong Zhang, Tingting Xu, Qinqin Cao, Aftab Shaukat, Ke Yue, Fang Liu, Haiju Dong, Shucheng Huang and 1 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in 3 Biotech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Luxi Lin *College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Pengfei Fu *College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Chaodong ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Tingting XuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Qinqin CaoCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Aftab ShaukatNational Center for International Research on Animal Genetics, Breeding and Reproduction (NCIRAGBR), Huazhong Agricultural University, Wuhan, 430070 China.
Ke YueCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Fang LiuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Haiju DongCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Shucheng HuangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.
Fuchun JianCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046 China.ORCID 0000-0002-0923-5901
Henan Agricultural University · CNHuazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aflatoxin B1 (AFB1) is an inevitable contaminant in animal feed and agricultural products, which seriously threatens the health of animals. However, there is currently no better diagnostic tool available than depending on clinical symptoms, pathophysiology, biochemical indicators, etc. Here, we profiled the fecal microbiomes of sheep exposed to and not exposed to AFB1 to identify potential non-invasive biomarkers of AFB1 intoxication by 16S rRNA gene sequencing technology, while measuring serum biochemical indexes. The results showed that the sheep exposed to AFB1 had significantly higher levels of the liver function indicators ALT (alanine transaminase) and AST (aspartate aminotransferase), and their microbial profiles were different from those of the CON (Control) group. In detail, the relative abundance of seven phyla and three genera were overrepresented in the AFB1 group from top 10 relative abundance. Importantly, we found that

Indexed as

Aflatoxin B1BifidobacteriumBiomarkerGut microbiota

Identifiers

PMID37990733
PMCPMC10657922
OpenAlexW4388808921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.