Evidence map›Paper›PMID 37990686›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2023

U-Net breast lesion segmentations for breast dynamic contrast-enhanced magnetic resonance imaging.

Lindsay Douglas, Roma Bhattacharjee, Jordan Fuhrman, Karen Drukker, Qiyuan Hu, Alexandra Edwards, Deepa Sheth, Maryellen Giger

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Predictive Performance of Radiomic Features Extracted from Breast MR Imaging in Postoperative Upgrading of Ductal Carcinoma in Situ to Invasive Carcinoma.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  5. Automatic breast lesion segmentation in phase preserved DCE-MRIs.Health information science and systems · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lindsay DouglasUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0002-4695-6441
Roma BhattacharjeeUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.
Jordan FuhrmanUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.
Karen DrukkerUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0001-6544-3476
Qiyuan HuUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0002-3326-6441
Alexandra EdwardsUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.
Deepa ShethUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.
Maryellen GigerUniversity of Chicago, Department of Radiology Committee on Medical Physics, Chicago, Illinois, United States.ORCID https://orcid.org/0000-0001-5482-9728
University of Chicago Medical Center · US

Funding

MEDICAL IMAGING AND DATA RESOURCE CENTER (MIDRC) YEAR 375N92020D00021 · NIBIB · UNIVERSITY OF CHICAGO · PI GIGER, MARYELLEN · 2021 to 2025
$16.6M
RESEARCH TRAINING IN MEDICAL PHYSICST32EB002103 · NIBIB · UNIVERSITY OF CHICAGO · PI ARMATO, SAMUEL G. · 2003 to 2019
$4.7M
Protected Radiomics Analysis Commons for Deep Learning in Biomedical DiscoveryS10OD025081 · OD · UNIVERSITY OF CHICAGO · PI GIGER, MARYELLEN L. · 2018 to 2018
$339k
High-Performance Computer Cluster for Image AnalysisS10RR021039 · NCRR · UNIVERSITY OF CHICAGO · PI NISHIKAWA, ROBERT M · 2007 to 2007
$230k
NCRR NIH HHS S10 RR021039NHLBI NIH HHS 75N92020D00021NIBIB NIH HHS T32 EB002103NIH HHS S10 OD025081
6 · The paper itself

Abstract

Purpose: Given the dependence of radiomic-based computer-aided diagnosis artificial intelligence on accurate lesion segmentation, we assessed the performances of 2D and 3D U-Nets in breast lesion segmentation on dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) relative to fuzzy c-means (FCM) and radiologist segmentations. Approach: Using 994 unique breast lesions imaged with DCE-MRI, three segmentation algorithms (FCM clustering, 2D and 3D U-Net convolutional neural networks) were investigated. Center slice segmentations produced by FCM, 2D U-Net, and 3D U-Net were evaluated using radiologist segmentations as truth, and volumetric segmentations produced by 2D U-Net slices and 3D U-Net were compared using FCM as a surrogate reference standard. Fivefold cross-validation by lesion was conducted on the U-Nets; Dice similarity coefficient (DSC) and Hausdorff distance (HD) served as performance metrics. Segmentation performances were compared across different input image and lesion types. Results: 2D U-Net outperformed 3D U-Net for center slice (DSC, HD Conclusions: Results suggest that 2D U-Net is promising in segmenting mass and nonmass enhancing breast lesions from first and second postcontrast subtraction MRIs and thus could be an effective alternative to FCM or 3D U-Net.

Indexed as

breast lesion segmentationbreast magnetic resonance imagingdeep learningfuzzy c-meansU-Net

Identifiers

PMID37990686
PMCPMC10658935
OpenAlexW4388826019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.