Evidence map›Paper›PMID 37990322›Full record

ArticleBMC pulmonary medicine2023

Current cough and sputum assessed by the cough and sputum assessment-questionnaire (CASA-Q) is associated with quality of life impairment in cystic fibrosis.

Lucie Charon, Claire Launois, Jeanne-Marie Perotin, Bruno Ravoninjatovo, Pauline Mulette, Julien Ancel, Thomas Guillard, Anaëlle Muggeo, Valérian Dormoy, Muriel Griffon and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02924818 (Cohort for Research and Innovation in Chronic Inflammatory Respiratory Diseases), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02924818 narecruitingnot on this map

Cohort for Research and Innovation in Chronic Inflammatory Respiratory Diseases: The RINNOPARI Project

TypeinterventionalSponsorCHU de ReimsRan2016 to 2036Enrolled225ConditionsChronic Inflammatory Pulmonary DiseasesArmsClinical assessment, questionnaires, pulmonary function test, blood test, microbiology
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Lucie CharonService des Maladies Respiratoires et Allergiques, CHU de Reims, Reims, France.
Claire LaunoisService des Maladies Respiratoires et Allergiques, CHU de Reims, Reims, France.
Jeanne-Marie PerotinService des Maladies Respiratoires et Allergiques, Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, P3Cell, U 1250, Reims, France.
Bruno RavoninjatovoService des Maladies Respiratoires et Allergiques, CHU de Reims, Reims, France.
Pauline MuletteService des Maladies Respiratoires et Allergiques, CHU de Reims, Reims, France.
Julien AncelService des Maladies Respiratoires et Allergiques, Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, P3Cell, U 1250, Reims, France.
Thomas GuillardLaboratoire de Bactériologie-Virologie-Hygiène hospitalière- Parasitologie-Mycologie, Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, P3Cell, Reims, U 1250, France.
Anaëlle MuggeoLaboratoire de Bactériologie-Virologie-Hygiène hospitalière- Parasitologie-Mycologie, Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, P3Cell, Reims, U 1250, France.
Valérian DormoyINSERM UMRS 1250, Université de Reims Champagne-Ardenne, Reims, France.
Muriel GriffonService des Maladies Respiratoires et Allergiques, CHU de Reims, Reims, France.
Sophie CarréService des Maladies Respiratoires et Allergiques, CHU de Reims, Reims, France.
François LebargyService des Maladies Respiratoires et Allergiques, Université de Reims Champagne-Ardenne, EA7509 IRMAIC, CHU de Reims, Reims, France.
Gaëtan DesléeService des Maladies Respiratoires et Allergiques, Université de Reims Champagne-Ardenne, INSERM, CHU de Reims, P3Cell, U 1250, Reims, France.
Sandra DuryService des Maladies Respiratoires et Allergiques, CHU de Reims, Reims, France. sdury@chu-reims.fr.
Centre Hospitalier Universitaire de Reims · FRInserm · FRImmuno-Régulation des Maladies Auto- immunes Inflammatoires et Cancer · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCough and sputum are major symptoms in cystic fibrosis (CF) that contribute to the impairment of quality of life.

methodsThis prospective single centre cross-sectional pilot study aimed to evaluate the results of a self-administered questionnaire assessing cough and sputum symptoms (2 domains), and their impact (2 domains) on daily activities in the previous week, named the Cough and Sputum Assessment Questionnaire (CASA-Q) in CF adult patients at stable state, and to analyse associations with clinical, functional, microbiological, radiological data, and two quality of life scales: the Cystic Fibrosis Questionnaire Revised (CFQ-R) and the Saint George Respiratory Questionnaire (SGRQ).

resultsForty-eight patients were included in this analysis (69% men; median age of 27.8 ± 8.1 years; median body mass index of 21.8 + 3.3 kg/m²; mean FEV

conclusionsCASA-Q allows the assessment of cough and sputum in CF adult patients and is associated with quality of life impairment. This simple easy-to-use tool could be used in routine clinical practice and in clinical studies to assess cough and sputum in CF patients.

trial registrationThe study was registered on ClinicalTrials.gov (NCT02924818, first posted on 5th October 2016).

Indexed as

Cystic FibrosisQuality of LifeAdultCoughCross-Sectional StudiesDyspneaFemaleHumansMalePilot ProjectsProspective StudiesSputumSurveys and QuestionnairesYoung AdultCASA-QCFQ-RCoughCystic fibrosisQuality of lifeSputum

Identifiers

PMID37990322
PMCPMC10664648
OpenAlexW4388858831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.