Evidence map›Paper›PMID 37990059›Full record

ArticleAngewandte Chemie (International ed. in English)2024

Engineered Glucose Oxidase-Carbon Nanotube Conjugates for Tissue-Translatable Glucose Nanosensors.

Shoichi Nishitani, Tiffany Tran, Andrew Puglise, Sounghyun Yang, Markita P Landry

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Enzyme-Activated MRI for In Vivo Glucose Imaging via a Biodegradable Chromium Nanoprobe.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Review
  7. Near-Infrared Fluorescent Single-Walled Carbon Nanotubes for Biosensing.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shoichi NishitaniDepartment of Chemical and Biomolecular Engineering, University of California, 94720, Berkeley, CA, USA.ORCID 0000-0001-6355-6952
Tiffany TranDepartment of Chemical and Biomolecular Engineering, University of California, 94720, Berkeley, CA, USA.
Andrew PugliseDepartment of Chemical and Biomolecular Engineering, University of California, 94720, Berkeley, CA, USA.
Sounghyun YangDepartment of Chemical and Biomolecular Engineering, University of California, 94720, Berkeley, CA, USA.
Markita P LandryDepartment of Chemical and Biomolecular Engineering, University of California, 94720, Berkeley, CA, USA.ORCID 0000-0002-5832-8522
University of California, Berkeley · USQB3 · US

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
Imaging presynaptic correlates of cocaine locomotor sensitization with near infrared catecholamine nanosensorsR03DA052810 · NIDA · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2021 to 2021
$223k
NIDA NIH HHS R03 DA052810NIGMS NIH HHS R35 GM128922
6 · The paper itself

Abstract

Continuous and non-invasive glucose monitoring and imaging is important for disease diagnosis, treatment, and management. However, glucose monitoring remains a technical challenge owing to the dearth of tissue-transparent glucose sensors. In this study, we present the development of near-infrared fluorescent single-walled carbon nanotube (SWCNT) based nanosensors directly functionalized with glucose oxidase (GOx) capable of immediate and reversible glucose imaging in biological fluids and tissues. We prepared GOx-SWCNT nanosensors by facile sonication of SWCNT with GOx in a manner that-surprisingly-does not compromise the ability of GOx to detect glucose. Importantly, we find by using denatured GOx that the fluorescence modulation of GOx-SWCNT is not associated with the catalytic oxidation of glucose but rather triggered by glucose-GOx binding. Leveraging the unique response mechanism of GOx-SWCNT nanosensors, we developed catalytically inactive apo-GOx-SWCNT that enables both sensitive and reversible glucose imaging, exhibiting a ΔF/F

Indexed as

Biosensing TechniquesNanotubes, CarbonAnimalsBlood GlucoseBlood Glucose Self-MonitoringGlucoseGlucose OxidaseHumansMiceBlood GlucoseGlucoseGlucose OxidaseNanotubes, CarbonBiosensorsGlucoseGlucose OxidaseImaging AgentsSingle-Walled Carbon Nanotubes

Identifiers

PMID37990059
PMCPMC11003487
OpenAlexW4388912518

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.