Evidence map›Paper›PMID 37989910›Full record

ArticleJournal of biomolecular NMR2024

Uniform [

Alexander R Davis, Elijah T Roberts, I Jonathan Amster, Adam W Barb

Open access · greenAbstract read
In one paragraph

Article in Journal of biomolecular NMR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Production of isotope-labeled nanobody KN035 inMagnetic resonance letters · 2026
    Article
  2. Automated Assignment ofJournal of the American Society for Mass Spectrometry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander R DavisDepartment of Biochemistry and Molecular Biology, University of Georgia, 120 E. Green St, Davison Life Science Complex, Athens, GA, 30602, USA.ORCID http://orcid.org/0000-0002-0805-2740
Elijah T RobertsDepartment of Chemistry, University of Georgia, Athens, GA, USA.ORCID http://orcid.org/0009-0007-4196-6062
I Jonathan AmsterDepartment of Chemistry, University of Georgia, Athens, GA, USA.ORCID http://orcid.org/0000-0001-7523-5144
Adam W BarbDepartment of Biochemistry and Molecular Biology, University of Georgia, 120 E. Green St, Davison Life Science Complex, Athens, GA, 30602, USA. abarb@uga.edu.ORCID http://orcid.org/0000-0003-3290-8649
University of Georgia · US

Funding

Composition and structure of antibody receptors at the surface of primary human cells during immune activationU01AI148114 · NIAID · UNIVERSITY OF GEORGIA · PI BARB, ADAM WESLEY, MACE, EMILY MARGARET · 2020 to 2024
$2.0M
12 T FTICR-MS System for the Analysis of MetabolitesS10OD025118 · OD · UNIVERSITY OF GEORGIA · PI AMSTER, I JONATHAN · 2018 to 2018
$2.0M
NIAID NIH HHS U01 AI148114NIH HHS S10 OD025118NIH HHS U01 AI148114
6 · The paper itself

Abstract

Despite the prevalence and importance of glycoproteins in human biology, methods for isotope labeling suffer significant limitations. Common prokaryotic platforms do not produce mammalian post-translation modifications that are essential to the function of many human glycoproteins, including immunoglobulin G1 (IgG1). Mammalian expression systems require complex media and thus introduce significant costs to achieve uniform labeling. Expression with Pichia is available, though expertise and equipment requirements surpass E. coli culture. We developed a system utilizing Saccharomyces cerevisiae, [

Indexed as

Escherichia coliSaccharomyces cerevisiaeAnimalsGlycoproteinsHumansImmunoglobulin Fc FragmentsImmunoglobulin GMammalsNuclear Magnetic Resonance, BiomolecularGlycoproteinsImmunoglobulin Fc FragmentsImmunoglobulin GAntibodyGlycoproteinIsotope labelingN-glycanYeast

Identifiers

PMID37989910
PMCPMC11025670
OpenAlexW4388857692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.