ArticleBMJ open respiratory research2023
Isolated small airways obstruction predicts future chronic airflow obstruction: a multinational longitudinal study.
Article in BMJ open respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Definitions of early COPD and predictors for disease progression: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- New spirometry recommendations from the Brazilian Thoracic Association - 2024 update.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025Guideline
- Artificial Intelligence-Enhanced Spirometry in Primary Healthcare: Opportunities for Early Detection of Small Airway Dysfunction.Healthcare (Basel, Switzerland) · 2026Review
- Associations Between Musculoskeletal Structural Parameters and Pulmonary Function in Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2026Article
- Expiratory time constant patterns reveal obstructive lung mechanics in non-obstructive spirometry.PLOS digital health · 2026Article
- Precision treatment of COPD based on novel imaging phenotypes: a treatable traits approach.Respiratory research · 2026Review
- Small airways obstruction predicts cardiovascular disease incidence: a longitudinal study of UK Biobank.ERJ open research · 2026Article
- Long-term variability of impulse oscillometry defined small airway dysfunction in participants with and without chronic obstructive pulmonary disease.BMJ open respiratory research · 2026Article
- Mapping the trajectory from pre-COPD to COPD: predictive value of symptoms, imaging, and physiologic abnormalities.Annals of the American Thoracic Society · 2026Article
- Lung function decline and incidence of chronic obstructive pulmonary disease in participants with spirometry-defined small airway dysfunction: a 15-year prospective cohort study in China.Respiratory research · 2025Article
- Bronchodilator responsiveness and future chronic airflow obstruction: a multinational longitudinal study.EClinicalMedicine · 2025Article
- Optimal spirometry thresholds for the prediction of chronic airflow obstruction: a multinational longitudinal study.ERJ open research · 2025Article
- Risk Factors for Acute Exacerbation in Patients with COPD Group E in Ningbo: Risk Analysis of Irregular Review, Cardiovascular Complications, and Lung Function Decline.International journal of chronic obstructive pulmonary disease · 2025Article
- Postbronchodilator Spirometry Reference Values Are Needed and Helpful for Identifying Pre-Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2024Article
- Identification of factors directly linked to incident chronic obstructive pulmonary disease: A causal graph modeling study.PLoS medicine · 2024Article
- Clinical features and 1-year outcomes of variable obstruction in participants with preserved spirometry: results from the ECOPD study in China.BMJ open respiratory research · 2024Article
- Aerodynamic Simulation of Small Airway Resistance: A New Imaging Biomarker for Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2024Article
- Mortality risk associated with occupational exposures in people with small airways obstruction.PloS one · 2024Article
Corrections and comments
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Authors and funding
23 authors at 14 institutions in 11 countries.
Funding
Abstract
backgroundChronic airflow obstruction is a key characteristic of chronic obstructive pulmonary disease. We investigated whether isolated small airways obstruction is associated with chronic airflow obstruction later in life.
methodsWe used longitudinal data from 3957 participants of the multinational Burden of Obstructive Lung Disease study. We defined isolated small airways obstruction using the prebronchodilator mean forced expiratory flow rate between 25% and 75% of the forced vital capacity (FVC) (FEF
resultsMedian follow-up time was 8.3 years. Chronic airflow obstruction was more likely to develop in participants with isolated small airways obstruction at baseline (FEF
conclusionMeasurements of small airways obstruction can be used as early markers of future obstructive lung disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.