Evidence map›Paper›PMID 37989309›Full record

ArticleCurrent biology : CB2023

Predatory fireflies and their toxic firefly prey have evolved distinct toxin resistance strategies.

Lu Yang, Flora Borne, Anja Betz, Matthew L Aardema, Ying Zhen, Julie Peng, Regina Visconti, Mariana Wu, Bartholomew P Roland, Aaron D Talsma and 3 more

Open access · greenAbstract read
In one paragraph

Article in Current biology : CB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  6. Article
  7. Sensational site: the sodium pump ouabain-binding site and its ligands.American journal of physiology. Cell physiology · 2024
    Review
  8. Deceptive Seduction byInsects · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Lu YangDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.
Flora BorneDepartment of Biological Sciences, Columbia University, New York, NY 10027, USA.
Anja BetzDepartment of Applied Entomology, University of Hohenheim, 70599 Stuttgart, Germany.
Matthew L AardemaDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA; Department of Biology, Montclair State University, Montclair, NJ 07043, USA.
Ying ZhenDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA; School of Life Sciences, Westlake University, Hangzhou 310024, China.
Julie PengDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.
Regina ViscontiDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.
Mariana WuDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.
Bartholomew P RolandDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Aaron D TalsmaDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Michael J PalladinoDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Georg PetschenkaDepartment of Applied Entomology, University of Hohenheim, 70599 Stuttgart, Germany.
Peter AndolfattoDepartment of Biological Sciences, Columbia University, New York, NY 10027, USA. Electronic address: pa2543@columbia.edu.
Princeton University · USUniversity of Pittsburgh · USColumbia University · USUniversity of Hohenheim · DEMontclair State University · US

Funding

Parallel evolution at Na,K-ATPase: a model system for understanding constraints on the evolution of novel protein functions.R01GM115523 · NIGMS · PRINCETON UNIVERSITY · PI ANDOLFATTO, PETER · 2015 to 2024
$2.8M
Regulators of cytosolic protein quality control in aging and diseaseR21AG059385 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PALLADINO, MICHAEL JOHN · 2018 to 2019
$443k
NIA NIH HHS R21 AG059385NIGMS NIH HHS R01 GM115523
6 · The paper itself

Abstract

Toxic cardiotonic steroids (CTSs) act as a defense mechanism in many firefly species (Lampyridae) by inhibiting a crucial enzyme called Na

Indexed as

FirefliesPredatory BehaviorAnimalsBiological Evolutioncompensatory evolutioncompensatory substitutionstarget-site insensitivity

Identifiers

PMID37989309
PMCPMC10872512
OpenAlexW4388824859

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.