Evidence map›Paper›PMID 37988884›Full record

ArticleJournal of the mechanical behavior of biomedical materials2024

Physics-informed UNets for discovering hidden elasticity in heterogeneous materials.

Ali Kamali, Kaveh Laksari

Abstract read
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Optimal experimental design for repeatable hyperelastic material characterization.Journal of the mechanical behavior of biomedical materials · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ali KamaliDepartment of Biomedical Engineering, University of Arizona College of Engineering, Tucson, AZ, USA.
Kaveh LaksariDepartment of Biomedical Engineering, University of Arizona College of Engineering, Tucson, AZ, USA; Department of Aerospace and Mechanical Engineering, University of Arizona College of Engineering, Tucson, AZ, USA; Department of Mechanical Engineering, University of California Riverside, Riverside, CA, USA. Electronic address: klaksari@engr.ucr.edu.

Funding

Enhanced Clinical Diagnosis through Imaging and Modeling: A Machine Learning Data Fusion FrameworkR21EB032187 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BABAEE, HESSAM, LAKSARI, KAVEH · 2021 to 2023
$636k
NIBIB NIH HHS R21 EB032187
6 · The paper itself

Abstract

Soft biological tissues often have complex mechanical properties due to variation in structural components. In this paper, we develop a novel UNet-based neural network model for inversion in elasticity (El-UNet) to infer the spatial distributions of mechanical parameters from strain maps as input images, normal stress boundary conditions, and domain physics information. We show superior performance - both in terms of accuracy and computational cost - by El-UNet compared to fully-connected physics-informed neural networks in estimating unknown parameters and stress distributions for isotropic linear elasticity. We characterize different variations of El-UNet and propose a self-adaptive spatial loss weighting approach. To validate our inversion models, we performed various finite-element simulations of isotropic domains with heterogenous distributions of material parameters to generate synthetic data. El-UNet is faster and more accurate than the fully-connected physics-informed implementation in resolving the distribution of unknown fields. Among the tested models, the self-adaptive spatially weighted models had the most accurate reconstructions in equal computation times. The learned spatial weighting distribution visibly corresponded to regions that the unweighted models were resolving inaccurately. Our work demonstrates a computationally efficient inversion algorithm for elasticity imaging using convolutional neural networks and presents a potential fast framework for three-dimensional inverse elasticity problems that have proven unachievable through previously proposed methods.

Indexed as

Elasticity Imaging TechniquesNeural Networks, ComputerAlgorithmsElasticityFinite Element AnalysisDeep learningElasticity imagingModel-based elastographyTissue biomechanics

Identifiers

PMID37988884
PMCPMC10842800

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.