Evidence map›Paper›PMID 37987951›Full record

ArticleHepatology international2024

Planning, implementing, and evaluating Hepatitis C virus elimination via collaborative community-based care cascade: age-period-cohort model for estimating demand from antecedent anti-HCV survey.

Ting-Yu Lin, Hsiao-Hsuan Jen, Tsung-Hui Hu, Yu-Chin Yao, Tony Hsiu-Hsi Chen, Amy Ming-Fang Yen, Yen-Po Yeh

Abstract read
In one paragraph

Article in Hepatology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ting-Yu Lin *Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Hsiao-Hsuan Jen *New Doctors, Ltd., Taipei, Taiwan.
Tsung-Hui HuDivision of Hepato-Gastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Yu-Chin YaoChanghua County Public Health Bureau, No.162, Sec. 2, Jhongshan Rd, Changhua City, Changhua County, 500, Taiwan.
Tony Hsiu-Hsi ChenGraduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Amy Ming-Fang YenSchool of Oral Hygiene, College of Oral Medicine, Taipei Medical University, No. 250, Wu-Hsin Street, Taipei, 110, Taiwan. amyyen@tmu.edu.tw.
Yen-Po YehChanghua County Public Health Bureau, No.162, Sec. 2, Jhongshan Rd, Changhua City, Changhua County, 500, Taiwan. yeh.leego@gmail.com.ORCID http://orcid.org/0000-0002-1091-387X

Funding

Ministry of Science and Technology, Taiwan 111-2118-M-002 -004 -MY2Ministry of Science and Technology, Taiwan 111-2118-M-038 -002 -MY2Ministry of Science and Technology, Taiwan 111-2811-M-002 -061 -MY2
6 · The paper itself

Abstract

backgroundEstimating the demand for HCV care cascade plays an important role in planning, monitoring, and assessing the performance of introducing a new community-based hepatitis C virus (HCV) elimination program but such an analytic and systematic approach has been barley addressed.

methodsA new collaborative care program for HCV elimination in the Changhua Community of Taiwan has been offered to a total of 895,353 residents since 2018. To grasp the variation of demand for HCV care cascade across demographic and geographic features in the planning stage, we applied the age-period-cohort spatial model to the antecedent anti-HCV survey enrolling 123,617 participants aged 30 years or older between 2005 and 2018. Based on this precise denominator, we then employed a "before-and-after" study design to routinely evaluate whether the WHO criteria of 90% RNA positive diagnosis and 80% successful treatments could be reached.

resultsThe overall demand for HCV care cascade was 4.28% (HCV infection) of the underlying population but a declining trend was noted. The early cohort had a higher demand, whereas the demand of the young cohort decreased with each passing year. The demand also differed by township. The demand, allowing for these variations, for antiviral treatment was 22,362, yielding the WHO target of 12,880 for achieving HCV elimination. With 11,844 successful treatments, the effectiveness of elimination has already reached 92% (11,844/12,880) by the end of 2022.

conclusionsThe demand for HCV care cascade allows health care decision-makers to timely and properly assess the performance of a novel community-based collaborative care program in achieving HCV elimination.

Indexed as

Hepatitis CHepatitis C, ChronicAntiviral AgentsHepacivirusHumansRNATaiwanAntiviral AgentsRNAAge–period–cohort modelCommunity-based screening programHCV care cascadeHepatitis C elimination

Identifiers

PMID37987951
PMCPMC11014808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.