Evidence map›Paper›PMID 37987950›Full record

ArticleApplied biochemistry and biotechnology2024

Evaluation of Developmental Toxicity and Oxidative Stress Caused by Zinc Oxide Nanoparticles in Zebra Fish Embryos/ Larvae.

Uvarajan Deenathayalan, Ravichandran Nandita, Krishnamoorthy Kavithaa, Vengamuthu Subramaniyan Kavitha, Chandramohan Govindasamy, Khalid S Al-Numair, Mohammed A Alsaif, Yong Pil Cheon, Narayanasamy Arul, Durairaj Brindha

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In one paragraph

Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Uvarajan DeenathayalanDepartment of Biochemistry, PSG College of Arts & Science, Coimbatore, Tamil Nadu, India.
Ravichandran NanditaDisease Proteomics Laboratory, Department of Zoology, Bharathiar University, Coimbatore, Tamil Nadu, India.
Krishnamoorthy KavithaaDepartment of Biotechnology, Hindusthan College of Arts & Science, Coimbatore, Tamil Nadu, India.
Vengamuthu Subramaniyan KavithaDepartment of Zoology, Vellalar College for Women, Thindal, Erode, 638012, Tamil Nadu, India.
Chandramohan GovindasamyDepartment of Community Health Sciences, College of Applied Medical Sciences, KingSaud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
Khalid S Al-NumairDepartment of Community Health Sciences, College of Applied Medical Sciences, KingSaud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
Mohammed A AlsaifDepartment of Community Health Sciences, College of Applied Medical Sciences, KingSaud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
Yong Pil CheonDivision of Developmental Biology and Physiology, Department of Biotechnology, Sungshin University, Seoul, 02844, South Korea.
Narayanasamy ArulDisease Proteomics Laboratory, Department of Zoology, Bharathiar University, Coimbatore, Tamil Nadu, India.
Durairaj BrindhaDepartment of Biochemistry, PSG College of Arts & Science, Coimbatore, Tamil Nadu, India. publicationbiochemistry@gmail.com.
King Saud University · SABharathiar University · INHindustan Institute of Technology and Science · INSungshin Women's University · KR

Funding

Researchers Supporting Project RSPD2023R712
6 · The paper itself

Abstract

Zinc oxide nanoparticles (ZnO NPs) are used in various fields, including biological ones. ZnO NPs are eventually disposed of in the environment where they may affect natural systems, and there is no international law to regulate their manufacture, usage, and disposal. Hence, this present study is carried out to synthesise a more non-toxic and bioactive ZnO NPs from the marine algae Sargassum polycystum. The ZnO NPs were biologically produced using the marine algae Sargassum polycystum. The dynamic light scattering result describes that synthesised particles' average size is about 100 nm in diameter. Transmission electron microscopy (TEM) analysis demonstrated the rod-like morphology of ZnO NPs. Fourier tranform-infrared spectroscopy (FT-IR) results revealed the presence of functional groups in ZnO NPs. The selected area electron diffraction (SAED) results strongly suggested the ZnO NPs crystallinity. ZnO NPs surface morphology and compositions were identified by scanning electron microscopy (SEM- EDX) values. To analyse the toxicity of synthesised nanoparticles, zebra fish larvae were used, which involved subjecting embryos to various ZnO NPs concentrations at 1 hpf and analysing the results at 96 hpf. The 60 and 80 ppm sub-lethal doses were chosen for further studies based on the LC

Indexed as

LarvaMetal NanoparticlesOxidative StressZebrafishZinc OxideAnimalsEmbryo, NonmammalianZinc OxideNanotoxicityTetratogenicityZebra fish embryotoxicity test (ZET)Zinc accumulationZinc oxide nanoparticles

Identifiers

PMID37987950
OpenAlexW4388865842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.