Evidence map›Paper›PMID 37987923›Full record

ArticleEuropean journal of applied physiology2024

Association of central blood pressure with an exaggerated blood pressure response to exercise among elite athletes.

Astrid Most, Lutz Kraushaar, Oliver Dörr, Stanislav Keranov, Sophie Hoelscher, Rebecca Weber, Ebru Akdogan, Vincent Groesser, Faeq Husain-Syed, Holger Nef and 2 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Prognostic value of exercise blood pressure: role of fitness and exercise training.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Astrid MostDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Lutz KraushaarAdiphea GmbH, Werbach, Germany.
Oliver DörrDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Stanislav KeranovDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Sophie HoelscherDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Rebecca WeberDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Ebru AkdoganDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Vincent GroesserDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Faeq Husain-SyedDepartment of Internal Medicine, Member of the German Center for Lung Research, Universities of Giessen and Marburg Lung Center, Justus Liebig University Giessen, Giessen, Germany.
Holger NefDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Christian W HammDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Pascal BauerDepartment of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany. pascal.bauer@innere.med.uni-giessen.de.ORCID http://orcid.org/0000-0002-6036-8689
Justus-Liebig-Universität Gießen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe systolic blood pressure/workload (SBP/MET) slope was recently reported to be a reliable parameter to identify an exaggerated blood pressure response (eBPR) in the normal population and in athletes. However, it is unclear whether an eBPR correlates with central blood pressure (CBP) and vascular function in elite athletes.

methodsWe examined 618 healthy male elite athletes (age 25.8 ± 5.1 years) of mixed sports with a standardized maximum exercise test. CBP and vascular function were measured non-invasively with a validated oscillometric device. The SBP/MET slope was calculated and the threshold for an eBPR was set at > 6.2 mmHg/MET. Two groups were defined according to ≤ 6.2 and > 6.2 mmHg/MET, and associations of CBP and vascular function with the SBP/MET slope were compared for each group.

resultsAthletes with an eBPR (n = 180, 29%) displayed a significantly higher systolic CBP (102.9 ± 7.5 vs. 100 ± 7.7 mmHg, p = 0.001) but a lower absolute (295 ± 58 vs. 384 ± 68 W, p < 0.001) and relative workload (3.14 ± 0.54 vs. 4.27 ± 1.1 W/kg, p < 0.001) compared with athletes with a normal SBP/MET slope (n = 438, 71%). Systolic CBP was positively associated with the SBP/MET slope (r = 0.243, p < 0.001). In multiple logistic regression analyses, systolic CBP (odds ratio [OR] 1.099, 95% confidence interval [CI] 1.045-1.155, p < 0.001) and left atrial volume index (LAVI) (OR 1.282, CI 1.095-1.501, p = 0.002) were independent predictors of an eBPR.

conclusionSystolic CBP and LAVI were independent predictors of an eBPR. An eBPR was further associated with a lower performance level, highlighting the influence of vascular function on the BPR and performance of male elite athletes.

Indexed as

HypertensionSportsAdultAthletesBlood PressureExerciseExercise TestHumansMaleYoung AdultCentral blood pressureElite athletesExaggerated blood pressurePulse wave analysisSBP/MET slopeVascular function

Identifiers

PMID37987923
PMCPMC10955016
OpenAlexW4388861716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.