Evidence map›Paper›PMID 37987602›Full record

ArticleeLife2023

Indole produced during dysbiosis mediates host-microorganism chemical communication.

Rui-Qiu Yang, Yong-Hong Chen, Qin-Yi Wu, Jie Tang, Shan-Zhuang Niu, Qiu Zhao, Yi-Cheng Ma, Cheng-Gang Zou

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Bacterial metabolism of tryptophan causes toxicity inbioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Use ofBiomolecules · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rui-Qiu Yang *State key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, China.
Yong-Hong Chen *State key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, China.
Qin-Yi Wu *Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Traditional Chinese Medicine, Kunming, China.
Jie Tang *State key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, China.
Shan-Zhuang NiuState key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, China.
Qiu ZhaoState key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, China.
Yi-Cheng MaState key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, China.
Cheng-Gang ZouState key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, China.ORCID 0000-0001-5519-4402
Yunnan University · CNYunnan University of Traditional Chinese Medicine · CN

Funding

Foundation for Innovative Research Groups of the National Natural Science Foundation of China 31900420Foundation for Innovative Research Groups of the National Natural Science Foundation of China 32260021Foundation for Innovative Research Groups of the National Natural Science Foundation of China the National Natural Science Foundation of China,31900420Foundation for Innovative Research Groups of the National Natural Science Foundation of China the National Natural Science Foundation of China,32260021Foundation for Innovative Research Groups of the National Natural Science Foundation of China the National Natural Science Foundation of China,U1802233Foundation for Innovative Research Groups of the National Natural Science Foundation of China U1802233Ministry of Science and Technology of the People's Republic of China 2022YFD1400700Ministry of Science and Technology of the People's Republic of China the National Key R&D Program of China, 2022YFD1400700Yunnan Characteristic Plant Extraction Laboratory 2022YKZY006Yunnan Characteristic Plant Extraction Laboratory Independent research fund,2022YKZY006Yunnan Province of China 202001BC070004Yunnan Province of China he Major Science and Technology Project in Yunnan Province of China, 202001BC070004
6 · The paper itself

Abstract

An imbalance of the gut microbiota, termed dysbiosis, has a substantial impact on host physiology. However, the mechanism by which host deals with gut dysbiosis to maintain fitness remains largely unknown. In

Indexed as

Caenorhabditis elegans ProteinsAnimalsBacteriaCaenorhabditis elegansDysbiosisEscherichia coliIndolesLongevityCaenorhabditis elegans ProteinsIndolesbiochemistryC. eleganschemical biologyDAF-16E. coligut dysbiosisindoleinfectious diseasemicrobiologyTRPA-1

Identifiers

PMID37987602
PMCPMC10691800
OpenAlexW4388869823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.