Evidence map›Paper›PMID 37987341›Full record

ArticleTomography (Ann Arbor, Mich.)2023

The Tomosynthesis Broken Halo Sign: Diagnostic Utility for the Classification of Newly Diagnosed Breast Tumors.

Johannes Deeg, Michael Swoboda, Daniel Egle, Verena Wieser, Afschin Soleiman, Valentin Ladenhauf, Malik Galijasevic, Birgit Amort, Silke Haushammer, Martin Daniaux and 1 more

Open access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Johannes DeegDepartment of Radiology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.ORCID 0000-0002-5139-4287
Michael SwobodaDepartment of Radiology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Daniel EgleDepartment of Gynecology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Verena WieserDepartment of Gynecology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Afschin SoleimanInstitute for Pathology, INNPath, University Hospital Tirol Kliniken, Anichstraße 35, 6020 Innsbruck, Austria.
Valentin LadenhaufDepartment of Radiology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Malik GalijasevicDepartment of Radiology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.ORCID 0000-0001-6577-0784
Birgit AmortDepartment of Radiology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Silke HaushammerDepartment of Radiology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Martin DaniauxDepartment of Radiology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Leonhard GruberDepartment of Radiology, Medical University Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Innsbruck Medical University · ATTirol Kliniken · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCompared to conventional 2D mammography, digital breast tomosynthesis (DBT) offers greater breast lesion detection rates. Ring-like hypodense artifacts surrounding dense lesions are a common byproduct of DBT. This study's purpose was to assess whether minuscule changes spanning this halo-termed the "broken halo sign"-could improve lesion classification.

methodsThis retrospective study was approved by the local ethics review board. After screening 288 consecutive patients, DBT studies of 191 female participants referred for routine mammography with a subsequent histologically verified finding of the breast were assessed. Examined variables included patient age, histological diagnosis, architectural distortion, maximum size, maximum halo depth, conspicuous margins, irregular shape and broken halo sign.

resultsWhile a higher halo strength was indicative of malignancy in general (

conclusionDBT-associated halo artifacts warrant thorough investigation in newly found breast lesions as they are associated with malignant tumors. The "broken halo sign"-the presence of small lines of variable diameter spanning the peritumoral areas of hypodensity-is a strong indicator of malignancy, especially in dense breasts, where architectural distortion may be obfuscated due to the surrounding tissue.

Indexed as

BreastBreast NeoplasmsFemaleHumansMammographyRetrospective Studiesbreast cancerbroken halo signtomosynthesis

Identifiers

PMID37987341
PMCPMC10661244
OpenAlexW4387902507

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.