Evidence map›Paper›PMID 37987329›Full record

Observational studyMedical sciences (Basel, Switzerland)2023

Association of Mediterranean Diet Adherence with Disease Progression Characteristics, Lifestyle Factors and Overall Survival in Gastric Cancer Patients.

Eleni Pavlidou, Sousana K Papadopoulou, Maria Tolia, Maria Mentzelou, Nikolaos Tsoukalas, Olga Alexatou, Theodora Tsiouda, Gerasimos Tsourouflis, Evmorfia Psara, Vasileios Bikos and 5 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medical sciences (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 3 countries.

Eleni PavlidouDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.ORCID 0000-0002-7764-3544
Sousana K PapadopoulouDepartment of Nutritional Sciences and Dietetics, Faculty of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece.ORCID 0000-0002-6408-6128
Maria ToliaDepartment of Radiotherapy, Faculty of Medicine, School of Health Sciences, University of Crete, 71003 Heraklion, Crete, Greece.ORCID 0000-0001-5822-4363
Maria MentzelouDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.
Nikolaos TsoukalasDepartment of Oncology, 401 General Army Hospital of Athens, 401 Geniko Stratiotiko Nosokomeio, 11525 Athens, Greece.ORCID 0000-0002-1455-1503
Olga AlexatouDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.
Theodora TsioudaOncology Department, "Theageneio" Anticancer Hospital, 54639 Thessaloniki, Greece.
Gerasimos TsourouflisSecond Department of Propedeutic Surgery, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Evmorfia PsaraDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.
Vasileios BikosOncology Department, "Theageneio" Anticancer Hospital, 54639 Thessaloniki, Greece.
Nikolaos KavantzasFirst Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Athens General Hospital "Laikon", 11527 Athens, Greece.
Ioly Kotta-LoizouDepartment of Life Sciences, Faculty of Natural Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.ORCID 0000-0003-3277-6359
Antonios DakanalisDepartment of Mental Health, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.ORCID 0000-0002-2328-3862
Theofanis VorvolakosDepartment of Psychiatry, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Constantinos GiaginisDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.ORCID 0000-0003-2878-4831
University of the Aegean · GRNational and Kapodistrian University of Athens · GRTheageneio General Hospital · GR401 General Military Hospital of Athens · GRAzienda Ospedaliera San Gerardo · ITDemocritus University of Thrace · GRImperial College London · GBInternational Hellenic University · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Mediterranean diet (MD) exerts a protective effect against cancer development and progression; however, the evaluation of its impact on gastric cancer still remains quite scarce. The present study aims to evaluate the association of MD adherence during the lifespan with disease progression characteristics, lifestyle factors and overall survival in gastric carcinoma patients.

methodsThis is an observational, cross-sectional study conducted on 186 gastric cancer patients followed up for a median time interval of 57 months or until death due to cancer disease. Tumor histopathological characteristics were retrieved from patients' medical records, while validated questionnaires assessing, immediately after the time of diagnosis, health-related quality of life, physical activity levels, sleep quality, depression, anxiety and MD adherence during the lifespan were used.

resultsHigher MD adherence during the lifespan was significantly associated with younger patients (

conclusionsHigher MD adherence during the lifespan was associated with less advanced tumor histopathology characteristics and favorable mental and physical lifestyle factors. Moreover, higher MD adherence during the lifespan was also independently correlated with longer overall survival in gastric carcinoma patients. Thus, adopting a healthy dietary pattern like the MD during the lifespan may act as a preventive agent in combination with a healthy lifestyle against gastric cancer development and progression.

Indexed as

CarcinomaDiet, MediterraneanStomach NeoplasmsDisease ProgressionHumansLife StyleQuality of LifeSmokinganxietybody mass indexdepressiondisease progressiongastric cancerMediterranean dietphysical activityquality of lifesleep qualitysurvival

Identifiers

PMID37987329
PMCPMC10660706
OpenAlexW4388694465

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.