Evidence map›Paper›PMID 37987184›Full record

ArticleObesity (Silver Spring, Md.)2023

Phenotyping children and adolescents with obesity using behavioral, psychological, and familial data.

Ruth G St Fleur, Marian Tanofsky-Kraff, Jack A Yanovski, Nicholas J Horton, Joel N Hirschhorn, Alison E Field

Open access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Ruth G St FleurDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0003-0989-981X
Marian Tanofsky-KraffDepartment of Medical and Clinical Psychology, Uniformed Services University of The Health Sciences, Bethesda, Maryland, USA.ORCID 0000-0003-3871-2233
Jack A YanovskiSection on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0001-8542-1637
Nicholas J HortonDepartment of Mathematics and Statistics, Amherst College, Amherst, Massachusetts, USA.
Joel N HirschhornProgram in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Alison E FieldDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.
Brown University · USAmherst College · USBroad Institute · USNational Institutes of Health · USUniformed Services University of the Health Sciences · US

Funding

Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI HU, FRANK B · 1992 to 2021
$25.0M
Physiology, Psychology, and Genetics of ObesityZIAHD000641 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI YANOVSKI, JACK A. · 2009 to 2025
$24.8M
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
Sexual Orientation and Obesity: Test of a Gendered Biopsychosocial ModelR01HD066963 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI AUSTIN, S BRYN · 2011 to 2015
$3.5M
Substance Disorders, Substance Use Treatment, and Sexual Orientation in YouthR01DA033974 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CORLISS, HEATHER L · 2013 to 2017
$3.5M
Phenotyping obesity using behavioral, psychological, physiological, familial, and genetic dataR01DK127585 · NIDDK · BROWN UNIVERSITY · PI HIRSCHHORN, JOEL N, ZIOBROWSKI, HANNAH · 2021 to 2024
$2.7M
The Development of Eating Disorders in Males and FemalesR01DK059570 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI FIELD, ALISON E · 2002 to 2006
$2.5M
Empirical eating disorder classification and validation using prospective studiesR01MH087786 · NIMH · BROWN UNIVERSITY · PI FIELD, ALISON E · 2010 to 2014
$2.5M
Impact of Violence on Obesity & Reproductive Axes in YouthR01HD049889 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2006 to 2010
$1.6M
Patient-oriented research in early life origins of CVDK24HL068041 · NHLBI · HARVARD PILGRIM HEALTH CARE, INC. · PI GILLMAN, MATTHEW W · 2001 to 2010
$1.4M
Intramural NIH HHS ZIA HD000641NHLBI NIH HHS K24 HL068041NHLBI NIH HHS U01 HL145386NICHD NIH HHS R01 HD049889NICHD NIH HHS R01 HD066963NIDA NIH HHS R01 DA033974NIDDK NIH HHS P30 DK046200NIDDK NIH HHS R01 DK059570NIDDK NIH HHS R01 DK127585NIMH NIH HHS R01 MH087786
6 · The paper itself

Abstract

objectiveThis prospective cohort study aimed to empirically derive phenotypes of children and adolescents with overweight and obesity.

methodsLatent class analyses using Mplus were carried out in the Growing Up Today Study. Information on participants' weight status, disordered eating behaviors, body image and weight concerns, depressive symptoms, and pubertal timing, as well as and maternal weight status, were included in the latent class analyses, which were stratified by sex. Mixed-effects regression was used to examine associations of the obesity phenotypes with adult weight gain, between age 20 and 35 years, independent of weight at beginning of follow-up and duration of follow-up.

resultsAmong the girls, four obesity phenotypes were identified: 1) "early puberty"; 2) "mothers with obesity"; 3) "high weight concerns"; and 4) "mixed." Only three phenotypes were identified among the boys: 1) "high weight concerns"; 2) "mothers with obesity"; and 3) "mixed." Participants who had overweight or obesity in childhood or adolescence gained more weight in young adulthood than their leaner peers, but the patterns of weight gain in young adulthood varied by phenotype of obesity in childhood and adolescence.

conclusionsThese results support examining risk factors for and treatment outcomes by obesity phenotypes.

Indexed as

Pediatric ObesityAdolescentAdultBody Mass IndexChildFemaleHumansMaleOverweightProspective StudiesRisk FactorsWeight GainYoung Adult

Identifiers

PMID37987184
PMCPMC10715712
OpenAlexW4388869899

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.