Evidence map›Paper›PMID 37987055›Full record

ReviewZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2023

[Bone/cartilage immunomodulating hydrogels: construction strategies and applications].

Maoyuan Li, Guoshuang Zheng, Jiahui Yang, Xiaofang Chen, Jianfeng Xu, Dewei Zhao

Open access · greenAbstract readReviewEnglish Abstract
In one paragraph

Review in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maoyuan LiZhongshan Clinical College of Dalian University, Dalian Liaoning, 116001, P. R. China.
Guoshuang ZhengDepartment of Orthopaedics, Zhongshan Hospital, Dalian University, Dalian Liaoning, 116001, P. R. China.
Jiahui YangDepartment of Orthopaedics, Zhongshan Hospital, Dalian University, Dalian Liaoning, 116001, P. R. China.
Xiaofang ChenZhongshan Clinical College of Dalian University, Dalian Liaoning, 116001, P. R. China.
Jianfeng XuZhongshan Clinical College of Dalian University, Dalian Liaoning, 116001, P. R. China.
Dewei ZhaoDepartment of Orthopaedics, Zhongshan Hospital, Dalian University, Dalian Liaoning, 116001, P. R. China.
Affiliated Zhongshan Hospital of Dalian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To review the research progress in the construction strategy and application of bone/cartilage immunomodulating hydrogels. Methods: The literature related to bone/cartilage immunomodulating hydrogels at home and abroad in recent years was reviewed and summarized from the immune response mechanism of different immune cells, the construction strategy of immunomodulating hydrogels, and their practical applications. Results: According to the immune response mechanism of different immune cells, the biological materials with immunoregulatory effect is designed, which can regulate the immune response of the body and thus promote the regeneration of bone/cartilage tissue. Immunomodulating hydrogels have good biocompatibility, adjustability, and multifunctionality. By regulating the physical and chemical properties of hydrogel and loading factors or cells, the immune system of the body can be purposively regulated, thus forming an immune microenvironment conducive to osteochondral regeneration. Conclusion: Immunomodulating hydrogels can promote osteochondral repair by affecting the immunomodulation process of host organs or cells. It has shown a wide application prospect in the repair of osteochondral defects. However, more data support from basic and clinical experiments is needed for this material to further advance its clinical translation process.

Indexed as

CartilageHydrogelsBone and BonesTissue EngineeringHydrogelsBone/cartilage tissue engineeringconstruction strategyhydrogelimmunomodulation

Identifiers

PMID37987055
PMCPMC10662399
OpenAlexW4388870118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.