Evidence map›Paper›PMID 37986982›Full record

ArticlebioRxiv : the preprint server for biology2023

Tissue-resident alveolar macrophages reduce O

M A Guttenberg, A T Vose, A Birukova, K Lewars, R I Cumming, M C Albright, J I Mark, C J Salazar, S Swaminathan, Z Yu and 8 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

M A GuttenbergDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.ORCID 0000-0003-1737-8002
A T VoseDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.ORCID 0000-0003-2745-7070
A BirukovaDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.ORCID 0000-0001-9168-138X
K LewarsDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.
R I CummingDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.
M C AlbrightDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.
J I MarkDepartment of Health Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-6499-2198
C J SalazarDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.
S SwaminathanDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL.ORCID 0000-0002-8292-122X
Z YuDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL.
Yu V SokolenkoDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL.
E BunyanDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL.
M J YaegerDivision of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH.
M B FesslerImmunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC.ORCID 0000-0002-8262-8613
L G QueDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.ORCID 0000-0001-9188-9244
K M GowdyDivision of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH.ORCID 0000-0002-7227-0697
A V MisharinDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL.ORCID 0000-0003-2879-3789
R M TigheDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC.ORCID 0000-0002-3465-9861
Duke University · USNorthwestern University · USThe Ohio State University · USNational Institute of Environmental Health Sciences · USUniversity of North Carolina at Chapel Hill · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Devalingam Mahalingam · 1993 to 2026
$153.9M
Tissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NAVDEEP S CHANDEL · 2015 to 2026
$26.9M
Technology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHARD G WUNDERINK · 2018 to 2026
$24.7M
The Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9M
Duke University Program in Environmental HealthT32ES021432 · NIEHS · DUKE UNIVERSITY · PI Akhenaton-Andrew Dhafir Jones, Joel Newman Meyer · 2013 to 2026
$4.0M
Cell Signaling of Host DefenseZ01ES102005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI FESSLER, MICHAEL B · 2006 to 2008
$3.3M
CXCL10/CXCR3 regulation of ozone-induced epithelial permeabilityR01ES027574 · NIEHS · DUKE UNIVERSITY · PI TIGHE, ROBERT MATTHEW · 2018 to 2022
$3.1M
Monocyte-derived alveolar macrophage drives inflammatory response to lung ozone exposureR01ES034350 · NIEHS · DUKE UNIVERSITY · PI Alexander Misharin, Robert Matthew Tighe · 2022 to 2026
$3.0M
Lung transplant injury drives chronic lung allograft dysfunction via recruitment ofmonocyte-derived alveolar macrophagesR01HL153312 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MISHARIN, ALEXANDER · 2020 to 2023
$2.9M
Targeting abnormal alveolar immune activation and failed epithelial repair in COVID-19R01HL158139 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BUDINGER, GR SCOTT, MISHARIN, ALEXANDER · 2022 to 2025
$2.9M
Novel role for CD163 in ozone induced alterations of pulmonary immunityR01ES028829 · NIEHS · OHIO STATE UNIVERSITY · PI GOWDY, KYMBERLY MAE · 2018 to 2022
$2.7M
FACSAria SORP Cell SorterS10OD011996 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GOOLSBY, CHARLES L. · 2012 to 2012
$482k
Intramural NIH HHS Z01 ES102005NCI NIH HHS P30 CA060553NHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL153312NHLBI NIH HHS R01 HL158139NIAID NIH HHS U19 AI135964NIA NIH HHS P01 AG049665NIA NIH HHS R21 AG075423NIEHS NIH HHS R01 ES027574NIEHS NIH HHS R01 ES028829NIEHS NIH HHS R01 ES034350NIEHS NIH HHS T32 ES021432NIH HHS S10 OD011996
6 · The paper itself

Abstract

Lung inflammation, caused by acute exposure to ozone (O

Identifiers

PMID37986982
PMCPMC10659406
OpenAlexW4388460360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.