Evidence map›Paper›PMID 37986930›Full record

ArticlebioRxiv : the preprint server for biology2023

Engineered Secretory Immunoglobulin A provides insights on antibody-based effector mechanisms targeting

Sonya Kumar Bharathkar, Michael J Miller, Beth M Stadtmueller

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sonya Kumar BharathkarDepartment of Biochemistry, University of Illinois Urbana-Champaign, Urbana, Illinois 61801 USA.ORCID 0000-0002-3637-4990
Michael J MillerCarle R. Woese Institute of Genomic Biology.ORCID 0000-0001-8579-1080
Beth M StadtmuellerDepartment of Biochemistry, University of Illinois Urbana-Champaign, Urbana, Illinois 61801 USA.ORCID 0000-0003-0637-3206
University of Illinois Urbana-Champaign · US

Funding

Investigating polymeric antibody assembly, structure, function and therapeutic potentialR01AI165570 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Beth M. Stadtmueller · 2021 to 2026
$3.4M
NIAID NIH HHS R01 AI165570
6 · The paper itself

Abstract

Secretory (S) Immunoglobin (Ig) A is the predominant mucosal antibody, which mediates host interactions with commensal and pathogenic microbes, including

Indexed as

agglutinationChimeric AntibodiesClostridioides difficilecross-linkingenchained growthSecretory Component (SC)Secretory Immunoglobin A (SIgA)Surface Layer protein (SLP)TcdATcdB

Identifiers

PMID37986930
PMCPMC10659285
OpenAlexW4388615800

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.