Evidence map›Paper›PMID 37986880›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Chemokine Receptor 2 Is A Theranostic Biomarker for Abdominal Aortic Aneurysms.

Santiago Elizondo-Benedetto, Sergio Sastriques-Dunlop, Lisa Detering, Batool Arif, Gyu Seong Heo, Deborah Sultan, Hannah Luehmann, Xiaohui Zhang, Xuefeng Gao, Kitty Harrison and 12 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 2 countries.

Santiago Elizondo-Benedetto
Sergio Sastriques-Dunlop
Lisa Detering
Batool Arif
Gyu Seong Heo
Deborah Sultan
Hannah Luehmann
Xiaohui ZhangORCID 0000-0002-4927-2117
Xuefeng Gao
Kitty Harrison
Dakkota Thies
Laura McDonald
Christophe Combadière
Chieh-Yu Lin
Yeona Kang
Jie Zheng
Joseph IppolitoORCID 0000-0003-1913-5573
Richard Laforest
Robert J Gropler
Sean J English
Mohamed A Zayed
Yongjian LiuORCID 0000-0002-1118-1535
Washington University in St. Louis · USCentre National de la Recherche Scientifique · FRHoward University · US

Funding

CCR2 Targeted Molecular Imaging and Treatment of Abdominal Aortic AneurysmsR01HL153436 · NHLBI · WASHINGTON UNIVERSITY · PI GROPLER, ROBERT J., ZAYED, MOHAMED A. · 2020 to 2023
$3.0M
PURCHASE OF A SIEMENS NEXT GENERATION PET/CTS10OD025214 · OD · WASHINGTON UNIVERSITY · PI WOODARD, PAMELA K · 2018 to 2018
$2.0M
NHLBI NIH HHS R01 HL153436NIH HHS S10 OD025214
6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is a degenerative vascular disease impacting aging populations with a high mortality upon rupture. There are no effective medical therapies to prevent AAA expansion and rupture. We previously demonstrated the role of the monocyte chemoattractant protein-1 (MCP-1) / C-C chemokine receptor type 2 (CCR2) axis in rodent AAA pathogenesis via positron emission tomography/computed tomography (PET/CT) using CCR2 targeted radiotracer

Identifiers

PMID37986880
PMCPMC10659515
OpenAlexW4388450267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.