Evidence map›Paper›PMID 37986846›Full record

ArticlebioRxiv : the preprint server for biology2023

Transcriptome analysis of the mouse fetal and adult rete ovarii and surrounding tissues.

Dilara N Anbarci, Rebecca O'Rourke, Yu Xiang, Derek T Peters, Blanche Capel, Jennifer McKey

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dilara N AnbarciDepartment of Cell Biology, Duke University Medical Center, Durham NC 27710.ORCID 0000-0003-0435-4749
Rebecca O'RourkeSection of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045.ORCID 0000-0003-1198-6963
Yu XiangDepartment of Cell Biology, Duke University Medical Center, Durham NC 27710.ORCID 0000-0001-8333-0782
Derek T PetersDepartment of Cell Biology, Duke University Medical Center, Durham NC 27710.ORCID 0000-0003-3334-6166
Blanche CapelDepartment of Cell Biology, Duke University Medical Center, Durham NC 27710.ORCID 0000-0002-6587-0969
Jennifer McKeySection of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045.ORCID 0000-0002-2640-1502
Duke University · USUniversity of Colorado Anschutz Medical Campus · US

Funding

OPPOSING PATHWAYS IN MAMMALIAN SEX DETERMINATIONR01HD039963 · NICHD · DUKE UNIVERSITY · PI CAPEL, BLANCHE · 2001 to 2025
$4.7M
Defining Mechanisms of Ovarian RescueR01HD090050 · NICHD · DUKE UNIVERSITY · PI CAPEL, BLANCHE · 2017 to 2021
$1.6M
Functions of the rete ovarii in ovary development, adult homeostasis, and female reproductive longevityR00HD103778 · NICHD · UNIVERSITY OF COLORADO DENVER · PI MCKEY, JENNIFER C · 2023 to 2025
$692k
Functions of the rete ovarii in ovary development, adult homeostasis, and female reproductive longevityK99HD103778 · NICHD · DUKE UNIVERSITY · PI MCKEY, JENNIFER C · 2021 to 2022
$207k
NICHD NIH HHS K99 HD103778NICHD NIH HHS R00 HD103778NICHD NIH HHS R01 HD039963NICHD NIH HHS R01 HD090050
6 · The paper itself

Abstract

The rete ovarii (RO) is an epithelial structure that arises during fetal development in close proximity to the ovary and persists throughout adulthood in mice. However, the functional significance of the RO remains elusive, and it has been absent from recent discussions of female reproductive anatomy. The RO comprises three distinct regions: the intraovarian rete (IOR) within the ovary, the extraovarian rete (EOR) in the periovarian tissue, and the connecting rete (CR) linking the EOR and IOR. We hypothesize that the RO plays a pivotal role in maintaining ovarian homeostasis and responding to physiological changes. To uncover the nature and function of RO cells, we conducted transcriptome analysis, encompassing bulk, single-cell, and nucleus-level sequencing of both fetal and adult RO tissues using the

Indexed as

ovaryrete ovariiRNA sequencingsingle-cell transcriptomicssingle-nucleus transcriptomics

Identifiers

PMID37986846
PMCPMC10659311
OpenAlexW4388461140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.