Evidence map›Paper›PMID 37986802›Full record

ArticlebioRxiv : the preprint server for biology2023

Degron-controlled protein degradation in

Glen E Cronan, Andrei Kuzminov

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Glen E CronanDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-7092-6595
Andrei KuzminovDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-7248-5164
University of Illinois Urbana-Champaign · US

Funding

Chromosomal death due to misincorporation of wrong material into DNAR01GM073115 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KUZMINOV, ANDREI · 2007 to 2022
$3.6M
NIGMS NIH HHS R01 GM073115
6 · The paper itself

Abstract

Protein degron tags have proven uniquely useful for characterization of gene function. Degrons mediate quick depletion, usually within minutes, of a protein of interest - allowing researchers to characterize cellular responses to the loss of function. To develop a general purpose degron tool in

Indexed as

ClpXP proteasedegronRecARuvBSspB adaptor

Identifiers

PMID37986802
PMCPMC10659297
OpenAlexW4388571209

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.