Evidence map›Paper›PMID 37986773›Full record

ArticlebioRxiv : the preprint server for biology2023

Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches.

John M Viola, Jiageng Liu, Aria Huang, Samuel H Grindel, Louis S Prahl, Alex J Hughes

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

John M ViolaDepartment of Bioengineering, University of Pennsylvania, Philadelphia, 19104, PA, USA.
Jiageng LiuDepartment of Bioengineering, University of Pennsylvania, Philadelphia, 19104, PA, USA.
Aria HuangDepartment of Bioengineering, University of Pennsylvania, Philadelphia, 19104, PA, USA.
Samuel H GrindelDepartment of Bioengineering, University of Pennsylvania, Philadelphia, 19104, PA, USA.
Louis S PrahlDepartment of Bioengineering, University of Pennsylvania, Philadelphia, 19104, PA, USA.ORCID 0000-0002-7811-6041
Alex J HughesDepartment of Bioengineering, University of Pennsylvania, Philadelphia, 19104, PA, USA.ORCID 0000-0001-6801-3455
University of Pennsylvania · USCalifornia Institute for Regenerative Medicine · US

Funding

TRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI GARY D. WU · 1997 to 2026
$32.5M
Graduate Training in Developmental BiologyT32HD083185 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Michael Granato, Foteini Mourkioti · 2015 to 2026
$4.0M
A developmental engineering toolbox for large-scale tissue engineeringR35GM133380 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Alex Hughes · 2019 to 2026
$3.3M
Engineering induction and assembly of human kidney tissueR01DK132296 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI HUGHES, ALEX · 2022 to 2025
$1.8M
Synthetic approaches to study cell polarity related kidney defectsF32DK126385 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI PRAHL, LOUIS SKJEI · 2020 to 2023
$209k
NICHD NIH HHS T32 HD083185NIDDK NIH HHS F32 DK126385NIDDK NIH HHS P30 DK050306NIDDK NIH HHS R01 DK132296NIGMS NIH HHS R35 GM133380
6 · The paper itself

Abstract

Controlling the time and place of nephron formation

Identifiers

PMID37986773
PMCPMC10659296
OpenAlexW4388599343

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.