Evidence map›Paper›PMID 37986763›Full record

ArticlebioRxiv : the preprint server for biology2023

Change in RhoGAP and RhoGEF availability drives transitions in cortical patterning and excitability in

Jonathan A Jackson, Marlis Denk-Lobnig, Katherine A Kitzinger, Adam C Martin

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jonathan A JacksonDepartment of Biology, Massachusetts Institute of Technology.
Marlis Denk-LobnigDepartment of Biophysics, University of Michigan.
Katherine A KitzingerDepartment of Biology, Massachusetts Institute of Technology.
Adam C MartinDepartment of Biology, Massachusetts Institute of Technology.
Massachusetts Institute of Technology · USHarvard University · USUniversity of Michigan · US

Funding

Tissue morphogenesis: From signals to forcesR35GM144115 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Adam Christopher Martin · 2022 to 2026
$3.0M
Investigating RhoA GTPase regulation in sculpting tissuesR01GM125646 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MARTIN, ADAM CHRISTOPHER · 2018 to 2021
$1.3M
NIGMS NIH HHS R01 GM125646NIGMS NIH HHS R35 GM144115
6 · The paper itself

Abstract

Actin cortex patterning and dynamics are critical for cell shape changes. These dynamics undergo transitions during development, often accompanying changes in collective cell behavior. While mechanisms have been established for individual cells' dynamic behaviors, mechanisms and specific molecules that result in developmental transitions in vivo are still poorly understood. Here, we took advantage of two developmental systems in

Indexed as

actomyosin cortexdevelopmentDrosophila egg chamberDrosophila embryoexcitabilityRhoA

Identifiers

PMID37986763
PMCPMC10659369
OpenAlexW4388461496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.