Evidence map›Paper›PMID 37986667›Full record

ArticleJournal of cachexia, sarcopenia and muscle2024

Sex- and age-specific normative values of lower extremity muscle power in Italian community-dwellers.

Helio Jose Coelho-Junior, Emanuele Marzetti, Anna Picca, Matteo Tosato, Riccardo Calvani, Francesco Landi

Open access · goldAbstract read
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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  7. Mitochondrial Quantity and Quality in Age-Related Sarcopenia.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Helio Jose Coelho-JuniorDepartment of Geriatrics and Orthopaedics, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0001-7482-9514
Emanuele MarzettiDepartment of Geriatrics and Orthopaedics, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0001-9567-6983
Anna PiccaFondazione Policlinico Universitario 'A. Gemelli' IRCCS, Rome, Italy.ORCID 0000-0001-7032-3487
Matteo TosatoFondazione Policlinico Universitario 'A. Gemelli' IRCCS, Rome, Italy.ORCID 0000-0001-5750-9746
Riccardo CalvaniFondazione Policlinico Universitario 'A. Gemelli' IRCCS, Rome, Italy.ORCID 0000-0001-5472-2365
Francesco LandiDepartment of Geriatrics and Orthopaedics, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0002-3472-1389
Università Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · ITLibera Università Maria SS. Assunta · IT

Funding

Carni SostenibiliCentro Studi Achille e Linda LorenzonDanone ItaliaErrekappaEuropean Commission NextGenerationEU(Age-ITspoke3).TheviewsandopinionsexpressedareonlythoseoftheauthorsanddonotnecessarilyreflectthoseoftheEuropeanUnionortheEuropeanCommission.NeithertheEuropeanUnionnortheEuropeanCommissioncanbeheldresponsibleforthem.FerrariniItalfarmacoItalia LongevaItalian Ministry of Health RicercaCorrente2023IVSILaborestMarche RegionNovartisNutriciaProActionSerenissimaUniversità Cattolica del Sacro Cuore D1.2020Università Cattolica del Sacro Cuore D1.2022Yakult
6 · The paper itself

Abstract

backgroundMuscle power is associated with health-related parameters. Simple equations were validated to estimate lower extremity muscle power measures based on the time to complete the five-repetition sit-to-stand test. The present study was conducted to provide lower extremity muscle power estimates and produce centile values in a large and relatively unselected population across a wide age spectrum.

methodsData were from the Longevity Check-up 7+ (Lookup 7+) project, an ongoing initiative conducted in unconventional settings (e.g., exhibitions, shopping centres and health promotion campaigns) across Italy to foster adoption of healthy lifestyles. Absolute, relative, allometric and specific muscle power measures of the lower extremities were estimated using validated formulas. Cross-sectional centile and normative values for muscle power measures from 18 to 81+ years were produced for the two sexes. Smoothed normative curves for men and women were constructed using the lambda-mu-sigma method.

resultsFrom 1 June 2015 to 31 October 2021, 13 515 participants were enrolled of whom 12 864 were eligible for the present study. Mean age was 55.9 years (standard deviation: 14.8 years; range: 18-98 years), and 7217 (56.%) were women. Absolute, relative, allometric and specific muscle power declined significantly with age. Specific patterns of decline were observed according to sex and muscle power parameter. Absolute muscle power peaked at 41-50 and 31-40 years in men and women, respectively. Afterwards, a decline rate of approximately 12% per decade was observed, regardless of sex. Relative muscle power showed the largest reduction with age, such that it was 40.6% and 46.4% smaller in men and women older than 80, respectively, compared with those aged 18-30 years. Age-related changes in allometric and specific muscle power measures were similar between men and women.

conclusionsData from the Lookup 7+ project indicate that lower extremity muscle power estimated using simple equations is significantly associated with age. Sex-specific patterns of decline in absolute and relative muscle power were observed with age. Allometric and specific muscle power declined at a similar rate in men and women.

Indexed as

LongevityLower ExtremityAdolescentAdultAge FactorsCross-Sectional StudiesFemaleHumansMaleMiddle AgedMusclesYoung Adultageingchair-stand testlifestyle interventionsnormative curvespercentilesphysical performance

Identifiers

PMID37986667
PMCPMC10834342
OpenAlexW4388870480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.