ArticleEye and vision (London, England)2023
Efficacy of small back optic zone design on myopia control for corneal refractive therapy (CRT): a one-year prospective cohort study.
Article in Eye and vision (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Pooled it
- The Impact of Back Optic Zone Design in Orthokeratology on Visual Performance.Translational vision science & technology · 2024Trial
- Analysis of the factors influencing the treatment zone area after overnight orthokeratology lens wearing.Journal of optometry · 2026Article
- Longitudinal Changes in Peripheral Refraction, Lag and Axial Length in Myopic Children Treated with Orthokeratology: A 12-Month Prospective Study.Children (Basel, Switzerland) · 2026Article
- Efficacy of different optical zone design with different myopia control for corneal refractive therapy (CRT): a one-year prospective cohort study.BMC ophthalmology · 2026Article
- Correlation between retinal defocus distribution and axial growth in myopic children wearing orthokeratology lenses.BMC ophthalmology · 2026Article
- Peripheral retinal defocus in children and adolescents with different refractive statuses and its relationship with refractive parameters.BMC ophthalmology · 2026Article
- The "Three-Tier Regulatory Network" of Orthokeratology in Myopia Control: Evidence Weight of Underlying Mechanisms, Controversies, and New Perspectives for Clinical Translation--A Review.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- The effect of orthokeratology lens optical zone size on myopia control in adolescents.Frontiers in medicine · 2026Article
- Corneal higher-order aberrations as key predictive indicators of axial elongation in myopic children with orthokeratology: a single-center prospective cohort study.Scientific reports · 2025Article
- Standardized Corneal Topography-Driven AI for Orthokeratology Fitting: A Hybrid Deep/Machine Learning Approach With Enhanced Generalizability.Translational vision science & technology · 2025Article
- Critical factors to predict efficacy of orthokeratology in inhibiting axial elongation in myopic children.BMC ophthalmology · 2025Article
- Efficacy of orthokeratology lens with the modified small treatment zone on myopia progression and visual quality: a randomized clinical trial.Eye and vision (London, England) · 2024Article
- Effects of different orthokeratology lens designs on slowing axial length elongation in children with myopia.International journal of ophthalmology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTo investigate the control effect on the axial length elongation using corneal refractive therapy (CRT) with different optical zone diameters (BOZDs). We also sought to compare the difference in higher-order aberrations (HOAs), treatment zone (TZ) size and Zernike defocus coefficient with different BOZDs and seek the optimal parameter for predicting axial elongation.
methodsThis prospective cohort study included 7- to 14-year-olds fitted with orthokeratology (ortho-K) lenses of 5-mm (5-mm group) or 6-mm BOZD (6-mm group). Axial length (AL), corneal topography, HOAs and Zernike defocus coefficient were obtained at baseline, and 1, 3, 6, 9 and 12 months follow-up visits. Multivariate regression analyses were used to explore the association between AL change and ocular biometric parameters. Receiver operating characteristic (ROC) curve analysis was used to determine the best diagnostic value for AL change in ocular biometric parameters.
resultsIn total, 301 participants completed the one-year follow-up. The mean AL change in the 5-mm group (0.13 ± 0.18 mm) was less than that in the 6-mm group (0.27 ± 0.15 mm) at the 12 months visit. The TZ size and decentration were smaller, while the Zernike defocus coefficient and HOAs were higher in the 5-mm group (all P < 0.05). Older age and smaller TZ size were protective factors against AL elongation in multiple regression. In predicting AL elongation, TZ diameter yielded an area under the ROC curve of 0.684 with a cut-off value of 3.82 mm.
conclusionThe 5-mm group showed 0.14 mm (51.8%) less axial elongation than the 6-mm group. The 5-mm BOZD produced a smaller TZ size, higher Zernike defocus coefficient and higher HOA after reshaping of the cornea. TZ size was the best predictor of AL elongation. TZ diameter less than 3.82 mm may lead to AL elongation less than 0.2 mm in one year.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.