Evidence map›Paper›PMID 37985749›Full record

ArticleGut microbes2023

Inhibition of intestinal FXR activity as a possible mechanism for the beneficial effects of a probiotic mix supplementation on lipid metabolism alterations and weight gain in mice fed a high fat diet.

Alice Beau, Bérengère Benoit, Mélanie Le Barz, Emmanuelle Meugnier, Armelle Penhoat, Catherine Calzada, Claudie Pinteur, Emmanuelle Loizon, Stéphanie Chanon, Aurélie Vieille-Marchiset and 7 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

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  16. Alleviating effect ofFrontiers in nutrition · 2025
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  17. Application ofMicroorganisms · 2024
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  19. GYY4137, as a slow-releasing HFrontiers in pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Alice BeauLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Bérengère BenoitLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Mélanie Le BarzLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Emmanuelle MeugnierLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Armelle PenhoatLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Catherine CalzadaLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Claudie PinteurLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Emmanuelle LoizonLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Stéphanie ChanonLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Aurélie Vieille-MarchisetLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Valérie SauvinetCentre de Recherche en Nutrition Humaine - Rhône-Alpes, INSERM, INRAe, Université Claude Bernard Lyon1, Hospices Civils de Lyon, Pierre Bénite, France.
Murielle GodetLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Fabienne LaugeretteLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Sophie HolowaczResearch & Development Department, PiLeJe Laboratoire, Paris, France.
Elsa JacoutonResearch & Development Department, PiLeJe Laboratoire, Paris, France.
Marie-Caroline MichalskiLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Hubert VidalLaboratoire CarMeN, INSERM U.1060, INRAe U. 1397, Université Claude Bernard Lyon1, Pierre Bénite, France.
Inserm · FRUniversité Claude Bernard Lyon 1 · FRLaboratoire CarMeN · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Supplementation with probiotics has emerged as a promising therapeutic tool to manage metabolic diseases. We investigated the effects of a mix of

Indexed as

Gastrointestinal MicrobiomeProbioticsAnimalsBile Acids and SaltsDiet, High-FatLipid MetabolismLiverMiceMice, Inbred C57BLRNA, MessengerTriglyceridesWeight GainBile Acids and SaltsRNA, MessengerTriglyceridesbifidobacterium animalisbile acidsgut microbiotahigh-fat dietintestinal FXR signalinglactobacillus gasserilipid metabolismMetabolic syndrome

Identifiers

PMID37985749
PMCPMC10730200
OpenAlexW4388850106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.