Evidence map›Paper›PMID 37985685›Full record

ArticleScientific reports2023

Self-supervised pre-training with contrastive and masked autoencoder methods for dealing with small datasets in deep learning for medical imaging.

Daniel Wolf, Tristan Payer, Catharina Silvia Lisson, Christoph Gerhard Lisson, Meinrad Beer, Michael Götz, Timo Ropinski

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  7. Pretraining on Chronic Lung Inflammatory Disease Datasets to Enhance Indeterminant Lung Cancer Classification using Masked Autoencoders.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
    Article
  8. Anatomically-guided masked autoencoder pre-training for aneurysm detection.IEEE Winter Conference on Applications of Computer Vision. IEEE Winter Conference on Applications of Computer Vision · 2026
    Article
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  12. Review
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  16. A unified approach to medical image segmentation by leveraging mixed supervision and self and transfer learning (MIST).Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daniel WolfVisual Computing Research Group, Institute of Media Informatics, Ulm University, Ulm, Germany. daniel.wolf@uni-ulm.de.
Tristan PayerVisual Computing Research Group, Institute of Media Informatics, Ulm University, Ulm, Germany.
Catharina Silvia LissonExperimental Radiology Research Group, Department for Diagnostic and Interventional Radiology, Ulm University Medical Center, Ulm, Germany.
Christoph Gerhard LissonExperimental Radiology Research Group, Department for Diagnostic and Interventional Radiology, Ulm University Medical Center, Ulm, Germany.
Meinrad BeerExperimental Radiology Research Group, Department for Diagnostic and Interventional Radiology, Ulm University Medical Center, Ulm, Germany.
Michael Götz *Experimental Radiology Research Group, Department for Diagnostic and Interventional Radiology, Ulm University Medical Center, Ulm, Germany.
Timo Ropinski *Visual Computing Research Group, Institute of Media Informatics, Ulm University, Ulm, Germany.
Universität Ulm · DEUniversity Hospital Ulm · DE

Funding

NUM 2.0 FKZ: 01KX2121
6 · The paper itself

Abstract

Deep learning in medical imaging has the potential to minimize the risk of diagnostic errors, reduce radiologist workload, and accelerate diagnosis. Training such deep learning models requires large and accurate datasets, with annotations for all training samples. However, in the medical imaging domain, annotated datasets for specific tasks are often small due to the high complexity of annotations, limited access, or the rarity of diseases. To address this challenge, deep learning models can be pre-trained on large image datasets without annotations using methods from the field of self-supervised learning. After pre-training, small annotated datasets are sufficient to fine-tune the models for a specific task. The most popular self-supervised pre-training approaches in medical imaging are based on contrastive learning. However, recent studies in natural image processing indicate a strong potential for masked autoencoder approaches. Our work compares state-of-the-art contrastive learning methods with the recently introduced masked autoencoder approach "SparK" for convolutional neural networks (CNNs) on medical images. Therefore, we pre-train on a large unannotated CT image dataset and fine-tune on several CT classification tasks. Due to the challenge of obtaining sufficient annotated training data in medical imaging, it is of particular interest to evaluate how the self-supervised pre-training methods perform when fine-tuning on small datasets. By experimenting with gradually reducing the training dataset size for fine-tuning, we find that the reduction has different effects depending on the type of pre-training chosen. The SparK pre-training method is more robust to the training dataset size than the contrastive methods. Based on our results, we propose the SparK pre-training for medical imaging tasks with only small annotated datasets.

Indexed as

Deep LearningDiagnostic ImagingHumansImage Processing, Computer-AssistedNeural Networks, ComputerRadiographySupervised Machine Learning

Identifiers

PMID37985685
PMCPMC10662445
OpenAlexW4388826394

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.