Evidence map›Paper›PMID 37985606›Full record

ArticleExperimental & applied acarology2023

Effect of Tagetes minuta essential oil on the central nervous system of unfed Rhipicephalus sanguineus sensu lato 'tropical lineage' ticks.

David Fernando Cepeda, Jociani Ascari, Murilo Silva de Oliveira, Gabriela Antonioli, Thiago Barcellos, Luis Adriano Anholeto, Pablo Henrique Nunes

Abstract read
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In one paragraph

Article in Experimental & applied acarology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

David Fernando CepedaInstituto Latino-Americano de Ciências da Vida e da Natureza, Universidade Federal da Integração Latino-Americana, Paraná, 85870-901, Brazil. davet9107@gmail.com.
Jociani AscariLaboratory of Chemistry, Universidade Tecnológica Federal do Paraná - UTFPR, Câmpus Santa Helena, Santa Helena, Paraná, Brazil.
Murilo Silva de OliveiraLaboratory of Chemistry, Universidade Tecnológica Federal do Paraná - UTFPR, Câmpus Santa Helena, Santa Helena, Paraná, Brazil.
Gabriela AntonioliUniversidade de Caixas do Sul, Francisco Getúlio Vargas St, 1130, Caxias do Sul, RS, Brazil.
Thiago BarcellosUniversidade de Caixas do Sul, Francisco Getúlio Vargas St, 1130, Caxias do Sul, RS, Brazil.
Luis Adriano AnholetoEmpresa Brasileira de Pesquisa Agropecuária - Embrapa Pecuária Sudeste, Rodovia Washington Luiz, Km 234 s/n, Fazenda Canchim, Caixa Postal 339, São Carlos, SP, 13560-970, Brazil.
Pablo Henrique NunesInstituto Latino-Americano de Ciências da Vida e da Natureza, Universidade Federal da Integração Latino-Americana, Paraná, 85870-901, Brazil.
Universidade de Caxias do Sul · BRUniversidade Federal da Integração Latino-Americana · BRUniversidade Tecnológica Federal do Paraná · BRBrazilian Agricultural Research Corporation · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 23422.016460/2017-41
6 · The paper itself

Abstract

Rhipicephalus sanguineus sensu lato 'tropical lineage' (Acari: Ixodidae) is considered a sanitary concern due to its role as a disease vector. Tick strains resistant to synthetic acaricides have caused difficulties in their control, besides synthetic acaricides are harmful to the environment and to the health of non-target animals. The research of plants with acaricidal and repellent properties has proved to be an efficient alternative in tick control. The genus Tagetes spp. excels for its use as traditional pest control in households and plantations and also for its potential as an acaricide against R. sanguineus under laboratory conditions. The first aim of the present study was to evaluate the effect of different doses of Tagetes minuta essential oil (TMEO) on the central nervous system (synganglion) in unfed R. sanguineus adults. The histological analysis of synganglion exposed to the different concentrations of TMEO and amitraz 12.5% (50% of the recommended dose in the package insert) showed a significant effect with signs of cell damage including volume increase, loss of shape, and vacuolization, in addition to chromatin alterations such as condensation, margination, and fragmentation. TMEO were analyzed by gas chromatography coupled with mass spectrometry showing the presence of 21 compounds that according to their chemical structure are classified as terpenoids. Among them (Z)-β-ocimene, ocimene, (Z)-tagetone, and verbenone were found in major quantities.

Indexed as

AcaricidesOils, VolatileRhipicephalus sanguineusTagetesAnimalsCentral Nervous SystemAcaricidesOils, VolatileAcaricideAlternativeControlGC-MSResistanceTerpenoids

Identifiers

PMID37985606
OpenAlexW4388824060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.