Evidence map›Paper›PMID 37985533›Full record

ArticleClinical rheumatology2024

Gender differences in patients with anti-MDA5-positive dermatomyositis: a cohort study of 251 cases.

Lu Cheng, Lingxiao Xu, Yan Xu, Fenghong Yuan, Ju Li, Min Wu, Zhanyun Da, Hua Wei, Lei Zhou, Songlou Yin and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sex-based differences in dermatomyositis: a retrospective study.Archives of dermatological research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 1 country.

Lu ChengDepartment of Rheumatology and Immunology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, Jiangsu, China.
Lingxiao XuDepartment of Rheumatology and Immunology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, Jiangsu, China.
Yan XuDepartment of Rheumatology and Immunology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, Jiangsu, China.
Fenghong YuanDepartment of Rheumatology and Immunology, Wuxi People's Hospital, Wuxi, Jiangsu, China.
Ju LiDepartment of Rheumatology and Immunology, Huai'an First People's Hospital, Huai'an, Jiangsu, China.
Min WuDepartment of Rheumatology and Immunology, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Zhanyun DaDepartment of Rheumatology and Immunology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.
Hua WeiDepartment of Rheumatology and Immunology, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu, China.
Lei ZhouDepartment of Rheumatology and Immunology, Changzhou No.2 People's Hospital, Changzhou, Jiangsu, China.
Songlou YinDepartment of Rheumatology and Immunology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Jian WuDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Yan LuDepartment of Rheumatology and Immunology, Jiangsu Province Hospital of Chinese Medicine, Nanjing, Jiangsu, China.
Dinglei SuDepartment of Rheumatology and Immunology, Nanjing First Hospital, Nanjing, Jiangsu, China.
Zhichun LiuDepartment of Rheumatology and Immunology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Lin LiuDepartment of Rheumatology and Immunology, Xuzhou Central Hospital, Xuzhou, Jiangsu, China.
Longxin MaDepartment of Rheumatology and Immunology, Yancheng No.1 People's Hospital, Yancheng, Jiangsu, China.
Xiaoyan XuDepartment of Rheumatology and Immunology, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China.
Huijie LiuDepartment of Rheumatology and Immunology, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu, China.
Tianli RenDepartment of Rheumatology and Immunology, Wuxi No.2 People's Hospital, Wuxi, Jiangsu, China.
Yinshan ZangDepartment of Rheumatology and Immunology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, Jiangsu, China. syzang@163.com.ORCID http://orcid.org/0000-0001-6812-8930
Nanjing Medical University · CNJiangsu Province Hospital · CNNantong University · CNSoochow University · CNChangzhou No.2 People's Hospital · CNHuaian First People’s Hospital · CNNorthern Jiangsu People's Hospital · CNThe First People's Hospital of Changzhou · CNThe First People’s Hospital of Lianyungang · CNWuxi No.2 People's Hospital · CNWuxi People's Hospital · CNXuzhou Central Hospital · CNXuzhou Medical College · CNZhongda Hospital Southeast University · CN

Funding

National Natural Science Foundation of China 82271844Suqian Sci & Tech Program KY202201
6 · The paper itself

Abstract

objectiveTo investigate the impact of sex differences on the clinical characteristics and prognosis of patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis (MDA5

methodsWe retrospectively analyzed a cohort of 251 patients with MDA5

resultsPatients in the male group had a significantly higher prevalence of heliotrope rash, V sign, severe interstitial lung disease (ILD), and rapidly progressive interstitial lung disease (RPILD) than those in the female group. Anti-Ro52 positivity, high CRP level and short disease were identified as independent risk factors for RPILD in both male and female groups by multivariate logistic regression analysis. The mortality rates of males and females were 33.8% and 22.0%, respectively, and the survival time of patients in the male group was shorter than that in the female group.

conclusionMale patients with MDA5

Indexed as

DermatomyositisExanthemaLung Diseases, InterstitialAutoantibodiesCohort StudiesDisease ProgressionFemaleHumansInterferon-Induced Helicase, IFIH1MalePrognosisRetrospective StudiesSex CharacteristicsSex FactorsAutoantibodiesInterferon-Induced Helicase, IFIH1Anti-MDA5 antibodyDermatomyositisMortalityRPILDSex

Identifiers

PMID37985533
OpenAlexW4388840059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.