Evidence map›Paper›PMID 37984997›Full record

ArticleGenome research2023

A naturally occurring variant of

Alexandra M Stendahl, Rashesh Sanghvi, Samuel Peterson, Karina Ray, Ana C Lima, Raheleh Rahbari, Donald F Conrad

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 13 citations in OpenAlex.

  1. Dynamics of mutators of arbitrary dominance in humans.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. A sibling study of variation in parental mutation rates.bioRxiv : the preprint server for biology · 2026
    Article
  5. What sets the mutation rate of a cell type in an animal species?bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Evolutionary Interplay of Somatic and Germline Mutation Rates.Annual review of biomedical data science · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. "Evolution of the mutation spectrum across a mammalian phylogeny".bioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alexandra M Stendahl *Division of Genetics, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA.
Rashesh Sanghvi *Cancer, Ageing and Somatic Mutation (CASM), Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom.ORCID 0000-0002-7703-9216
Samuel Peterson *Division of Genetics, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA.
Karina RayDivision of Genetics, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA.
Ana C LimaDivision of Genetics, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA.
Raheleh Rahbari *Cancer, Ageing and Somatic Mutation (CASM), Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom rr11@sanger.ac.uk conradon@ohsu.edu.
Donald F Conrad *Division of Genetics, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA; rr11@sanger.ac.uk conradon@ohsu.edu.ORCID 0000-0003-3828-8970
Oregon National Primate Research Center · USWellcome Sanger Institute · GB

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Multispecies NHP dGTEx Research CenterU24HG012483 · NHGRI · OREGON HEALTH & SCIENCE UNIVERSITY · PI KRISTIN ARDLIE, DONALD F. CONRAD · 2022 to 2026
$17.0M
Coordinating center for collaborative marmoset researchU24MH123696 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI DONALD F. CONRAD · 2020 to 2026
$4.6M
NHGRI NIH HHS U24 HG012483NIH HHS P51 OD011092NIMH NIH HHS U24 MH123696
6 · The paper itself

Abstract

As part of an ongoing genome sequencing project at the Oregon National Primate Research Center, we identified a rhesus macaque with a rare homozygous frameshift mutation in the gene methyl-CpG binding domain 4, DNA glycosylase (

Indexed as

Germ-Line MutationMacaca mulattaAnimalsEndodeoxyribonucleasesFemaleFrameshift MutationGerm CellsHumansMaleEndodeoxyribonucleases

Identifiers

PMID37984997
PMCPMC10760519
OpenAlexW4388818344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.