ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024
Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks.
Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Fibroblast-Mimetic Lignin Polymersomes for Logic-Gated Synthesis of Mechanically Reconfigurable Bioskins.Angewandte Chemie (International ed. in English) · 2026Article
- Functional Insertion of the Light-Induced Ion Pump KR2 into Block Copolymer Membranes.Biomacromolecules · 2026Article
- Peptide-Metal Cation Coacervate Microdroplets as Membrane-free Protocells with Enhanced Light-Induced Catalysis.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Vesicle-Templated Self-Assembly of Programmable Freestanding Multi-μm DNA Shells.Nano letters · 2026Article
- Bottom-Up Coacervate-Based Artificial Cells: Integrating Cellular Hallmarks into Complex Life-Like Systems.Angewandte Chemie (International ed. in English) · 2026Review
- Programmable Coacervates Based on Minimalist Sticker-Spacer Frameworks: Chemical Design, Functions, and Emerging Applications.ACS applied materials & interfaces · 2026Review
- Leaky by Design: Unlocking Polymersome Permeability Using Moderately Hydrophobic Polymer Blocks.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Riboswitch-controlled lipid conversion enables functional membrane asymmetry in artificial cells.Communications biology · 2026Article
- Dynamic Covalent Boronate Chemistry forJournal of the American Chemical Society · 2026Article
- Construction of Peptide Amphiphile-Coated Coacervates with Selective Permeability.ACS biomaterials science & engineering · 2026Article
- Bottom-up Strategies for Generating Polymer Protocells That Mimic Cellular Communication.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Nature-Inspired Enzymatic Cascades: Emerging Strategies for Sustainable Chemistry.Molecules (Basel, Switzerland) · 2026Review
- Internal Phase Separation in Synthetic DNA Condensates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Engineering Motile Coacervate Droplets via Nanomotor Stabilization.Journal of the American Chemical Society · 2025Article
- From Nano to Micro Polyion Complex Vesicles: Synthetic Cells with Membrane-Embedded Enzymes.ACS applied materials & interfaces · 2025Article
- Dendritic Membranized Coacervate Microdroplets: A Robust Platform for Synthetic-Living Cell Consortia.Journal of the American Chemical Society · 2025Article
- Building a Synthetic Cell Together.Nature communications · 2025Review
- Polymeric Giant Unilamellar Vesicles Support Longevity of Native Nuclei in Protocells.Small science · 2025Article
- Balancing Permeability and Stability: A Study of Hybrid Membranes for Synthetic Cells Using Lipids and PBd-Biomacromolecules · 2025Article
- Characterization and Optimization of Vesicle Properties in bioPISA: from Size Distribution to Post-Assembly Loading.Advanced biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The exponential growth of research on artificial cells and organelles underscores their potential as tools to advance the understanding of fundamental biological processes. The bottom-up construction from a variety of building blocks at the micro- and nanoscale, in combination with biomolecules is key to developing artificial cells. In this review, artificial cells are focused upon based on compartments where polymers are the main constituent of the assembly. Polymers are of particular interest due to their incredible chemical variety and the advantage of tuning the properties and functionality of their assemblies. First, the architectures of micro- and nanoscale polymer assemblies are introduced and then their usage as building blocks is elaborated upon. Different membrane-bound and membrane-less compartments and supramolecular structures and how they combine into advanced synthetic cells are presented. Then, the functional aspects are explored, addressing how artificial organelles in giant compartments mimic cellular processes. Finally, how artificial cells communicate with their surrounding and each other such as to adapt to an ever-changing environment and achieve collective behavior as a steppingstone toward artificial tissues, is taken a look at. Engineering artificial cells with highly controllable and programmable features open new avenues for the development of sophisticated multifunctional systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.